Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2022; 10(10): 3060-3068
Published online Apr 6, 2022. doi: 10.12998/wjcc.v10.i10.3060
Preventive online and offline health management intervention in polycystic ovary syndrome
Rui Liu, Min Li, Pei Wang, Man Yu, Zheng Wang, Guang-Zhong Zhang
Rui Liu, Guang-Zhong Zhang, Dermatological Department, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 101100, China
Rui Liu, Min Li, Pei Wang, Man Yu, Zheng Wang, Chinese Medicine Department, Beijing Luhe Hospital, Capital Medical University, Beijing 101100, China
Author contributions: Liu R and Zhang GZ designed this retrospective study; Liu R and Li M wrote this paper; Liu R, Li M, Wang P, Yu M, Wang Z and Zhang GZ were responsible for sorting the data; and all authors read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Luhe Hospital of Capital Medical University Institutional Review Board (Approval No. 2020-LHKY-016-02).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guang-Zhong Zhang, MD, Chief Doctor, Dermatological Department, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23 Back Street, Art Museum, Dongcheng District, Beijing 101100, China. zhangguangzhong@bizhongyi.com
Received: December 2, 2021
Peer-review started: December 2, 2021
First decision: January 10, 2022
Revised: January 24, 2022
Accepted: February 19, 2022
Article in press: February 19, 2022
Published online: April 6, 2022
ARTICLE HIGHLIGHTS
Research background

The clinical treatment of polycystic ovary syndrome (PCOS) according to western medicine is focused on using ovulation promoting drugs, which, due to side effects, are poorly tolerated and thus ineffective for some patients. The development of new therapies for PCOS that can potentially be combined, has become the target of future research. At this stage, with the rapid development of Internet medical care and big data, the online and offline (O2O) health management model has gradually become popular, and has a good development prospects. The Chinese and Western medicine health management model in the era of "Internet +" has achieved good results in the treatment of various chronic diseases. The O2O health management model based on the theoretical system of Chinese medicine preventive treatment has been used in patients with ovulatory disorders. It has a good effect and plays an important role in preventing the disease before it occurs, preventing the disease after the disease, and preventing the relapse after recovery.

Research motivation

We aimed to conduct clinical research on the application of an O2O health management model to intervene in PCOS of the kidney deficiency and phlegm-dampness type.

Research objectives

To confirm that the therapeutic effect of prophylactic O2O health management model on patients with PCOS is better than that of basic treatment alone, and it has significant advantages in improving clinical symptoms and prognosis.

Research methods

A total of 82 patients with PCOS of the kidney deficiency and phlegm dampness type were randomly divided into two groups. The treatment group was treated with oral Diane-35 for 3 mo and received preventive O2O medical health management for 6 mo. The control group was treated with oral Diane-35 for 3 mo and completed outpatient health education.

Research results

After treatment, the TCM syndrome score, acne score, and serum luteinizing hormone/follicle stimulating hormone level were significantly lower in the treatment group than in the control group. After 3 mo of treatment, the TCM syndrome curative effect index in the treatment group was 97.30% compared to 54.05% in the control group, whereas the total treatment effect in the treatment group was 91.89%, compared to 54.05% in the control group.

Research conclusions

An integrated therapeutic approach incorporating medication, TCM methods and social media is more effective than standard treatment for PCOS.

Research perspectives

In future research, it is necessary to further increase the level of health education and standardize the hospital management model to provide convenience for better patient service.