Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2022; 10(10): 3060-3068
Published online Apr 6, 2022. doi: 10.12998/wjcc.v10.i10.3060
Preventive online and offline health management intervention in polycystic ovary syndrome
Rui Liu, Min Li, Pei Wang, Man Yu, Zheng Wang, Guang-Zhong Zhang
Rui Liu, Guang-Zhong Zhang, Dermatological Department, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 101100, China
Rui Liu, Min Li, Pei Wang, Man Yu, Zheng Wang, Chinese Medicine Department, Beijing Luhe Hospital, Capital Medical University, Beijing 101100, China
Author contributions: Liu R and Zhang GZ designed this retrospective study; Liu R and Li M wrote this paper; Liu R, Li M, Wang P, Yu M, Wang Z and Zhang GZ were responsible for sorting the data; and all authors read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Luhe Hospital of Capital Medical University Institutional Review Board (Approval No. 2020-LHKY-016-02).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guang-Zhong Zhang, MD, Chief Doctor, Dermatological Department, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, No. 23 Back Street, Art Museum, Dongcheng District, Beijing 101100, China. zhangguangzhong@bizhongyi.com
Received: December 2, 2021
Peer-review started: December 2, 2021
First decision: January 10, 2022
Revised: January 24, 2022
Accepted: February 19, 2022
Article in press: February 19, 2022
Published online: April 6, 2022
Processing time: 117 Days and 2 Hours
Abstract
BACKGROUND

Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, hyperinsulinemia, ovarian polycystic changes, and irregular ovulation, often occurring in women of childbearing age for whom it can be a cause of infertility. Hypothalamus-pituitary-ovarian axis dysregulation is important in the pathogenesis of PCOS and the associated chronic excess of sex hormones can lead to cardiovascular and cerebrovascular diseases, diabetes, and malignancies such as endometrial cancer, and breast cancer. At present, most scholars agree that lifestyle interventions in conjunction with drug treatment can help PCOS patients achieve their goals of successful pregnancy and childbirth.

AIM

To investigate the clinical effect of an online and offline (O2O) preventive health management model on PCOS with kidney deficiency and phlegm dampness.

METHODS

A total of 82 patients with PCOS of the kidney deficiency and phlegm dampness type who were admitted to Beijing Luhe Hospital Affiliated to Capital Medical University from April 2019 to June 2020 were randomly divided into two groups. The treatment group was treated with oral Diane-35 for 3 mo and received preventive O2O medical health management for 6 mo (including eating and living, exercise, drug management). The control group was treated with oral Diane-35 for 3 mo and completed outpatient health education. The traditional Chinese medicine (TCM) syndrome score, acne score, hair score, sex hormone level and clinical effects were compared between the two groups before and after the intervention.

RESULTS

After treatment, the TCM syndrome score, acne score, and serum luteinizing hormone/follicle stimulating hormone level were significantly lower in the treatment group than in the control group (P < 0.05). After 3 mo of treatment, the TCM syndrome curative effect index in the treatment group was 97.30% compared to 54.05% in the control group (P < 0.05), whereas the total treatment effect in the treatment group was 91.89%, compared to 54.05% in the control group (P < 0.05).

CONCLUSION

An integrated therapeutic approach incorporating medication, TCM methods and social media is more effective than standard treatment for PCOS.

Keywords: Preventive treatment of disease; Online and offline mode; Health management; Kidney deficiency and phlegm dampness type; Chinese traditional medicine; Polycystic ovary syndrome

Core Tip: The clinical manifestations of polycystic ovary syndrome are oligomenorrhea, anovulation, ovarian polycystic changes, infertility, obesity, acne, and hirsutism. The effects of a preventive online and offline health management model on polycystic ovary syndrome patients are greater than simple basic treatment, and have significant advantages in improving clinical symptoms and outcomes.