Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2021; 9(8): 1996-2000
Published online Mar 16, 2021. doi: 10.12998/wjcc.v9.i8.1996
Mycobacterium abscessus infection after facial injection of argireline: A case report
Chao-Feng Chen, Jie Liu, Shuang-Shuang Wang, Yu-Fang Yao, Bo Yu, Xiao-Ping Hu
Chao-Feng Chen, Jie Liu, Shuang-Shuang Wang, Yu-Fang Yao, Bo Yu, Xiao-Ping Hu, Department of Dermatology & Venereology, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China
Author contributions: These authors contributed equally to this work and should be considered as joint first authors. Hu XP reviewed the data and consulted the authors; Chen CF and Liu J wrote the article and extracted the data; Wang SS, Yao YF, and Yu B revised and edited the article.
Supported by The Scientific Research Project of Peking University Shenzhen Hospital, No. JCYJ2018011 and the San-ming Project of Medicine in Shenzhen, No. SZSM201812059.
Informed consent statement: Informed written consent was obtained from the patient and her parents for the publication of this report and any accompanying images.
Conflict-of-interest statement: No conflict of interest is declared.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Ping Hu, PhD, Associate Professor, Department of Dermatology & Venereology, Peking University Shenzhen Hospital, No. 1120 Lianhua Road, Futian District, Shenzhen 518036, Guangdong Province, China. xiaoping7752@sohu.com
Received: November 23, 2020
Peer-review started: November 23, 2020
First decision: December 13, 2020
Revised: December 14, 2020
Accepted: January 15, 2021
Article in press: January 15, 2021
Published online: March 16, 2021
Processing time: 101 Days and 19.6 Hours
Abstract
BACKGROUND

The incidence of infection with Mycobacterium abscessus (M. abscessus) has increased in recent years. This increase is partly associated with invasive cosmetic procedures.

CASE SUMMARY

The purpose of this case summary is to increase clinicians' awareness of M. abscessus infection and reduce mycobacterial infection caused by cosmetic procedures. We report the case of a 45-year-old woman who received acetyl hexapeptide-8 (argireline) injections in the forehead and temples, and erythema, nodules, and abscesses appeared at the injection sites after one week. The pus specimens were examined by microbiological culture and confirmed to be positive for M. abscessus. Clarithromycin 500 mg twice daily and moxifloxacin 400 mg once daily were administered for 5 mo and the lesions gradually subsided.

CONCLUSION

We report here for the first time a case of infection with M. abscessus after argireline injection. This condition is easily misdiagnosed as a common bacterial infection. Microbiological examinations are helpful for diagnosis and standardized cosmetic procedures can prevent infection with M. abscessus.

Keywords: Argireline; Mycobacterium abscessus; Nontuberculous Mycobacterium; Infection; Injection; Antibiotic therapy; Case report

Core Tip: Mycobacterium abscessus (M. abscessus) is a rapidly growing nontubercul-ous mycobacterium that can lead to infections of the lung, lymph node, skin, and soft tissue. The incidence of infection with M. abscessus has increased in recent years. This increase is partly associated with invasive cosmetic procedures. We report here for the first time a case of infection with M. abscessus after argireline injection. The purpose of this case summary is to increase clinicians' awareness of M. abscessus infection and reduce mycobacterial infection caused by cosmetic procedures.