Zhang YS, Hu TC, Ye YC, Han JH, Li XJ, Zhang YH, Chen WZ, Chai HY, Pan X, Wang X, Yang YL. Carbon ion radiotherapy for synchronous choroidal melanoma and lung cancer: A case report. World J Clin Cases 2021; 9(33): 10374-10381 [PMID: 34904113 DOI: 10.12998/wjcc.v9.i33.10374]
Corresponding Author of This Article
Yan-Cheng Ye, PhD, Chief Doctor, Heavy Ion Center, Wuwei Cancer Hospital, No. 31 Sanitary Alley, Haizang Road, Wuwei 733000, Gansu Province, China. zlyyyyc@163.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Yan-Shan Zhang, Ting-Chao Hu, Yan-Cheng Ye, Xiao-Jun Li, Yi-He Zhang, Wei-Zuo Chen, Hong-Yu Chai, Xin Pan, Xin Wang, Yu-Ling Yang, Heavy Ion Center, Wuwei Cancer Hospital, Wuwei 733000, Gansu Province, China
Jin-Hua Han, Department of Ophthalmology, Wuwei Cancer Hospital, Wuwei 733000, Gansu Province, China
Author contributions: Zhang YS and Hu TC designed the experiment; Ye YC drafted the manuscript; Han JH, Li XJ and Zhang YH collected the data; Chen WZ and Chai HY analyzed and interpreted the data; Pan X, Wang X and Yang YL wrote the article.
Supported byKey R&D plan of Science and Technology Program of Gansu Province, China, No. 19YF3FH001.
Informed consent statement: Informed written consent was obtained from the patient.
Conflict-of-interest statement: No conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan-Cheng Ye, PhD, Chief Doctor, Heavy Ion Center, Wuwei Cancer Hospital, No. 31 Sanitary Alley, Haizang Road, Wuwei 733000, Gansu Province, China. zlyyyyc@163.com
Received: August 12, 2021 Peer-review started: August 12, 2021 First decision: September 2, 2021 Revised: September 8, 2021 Accepted: September 30, 2021 Article in press: September 30, 2021 Published online: November 26, 2021 Processing time: 102 Days and 2.2 Hours
Abstract
BACKGROUND
Despite being the most common intraocular malignancy among adults, choroidal melanoma is a rare cancer type, even more so when accompanied by lung cancer. We report a patient with synchronous choroid melanoma and lung cancer treated with carbon ion radiotherapy (CIRT).
CASE SUMMARY
A 41-year-old woman was transferred to our center with a diagnosis of choroidal melanoma in her right eye. During the examination, we found a right lung tumor that was histologically diagnosed as lung cancer. The patient was treated with CIRT for both malignant neoplasms. The CIRT dose was 70 photon equivalent doses (GyE) in five fractions for the right eye choroidal melanoma and 72 GyE in 16 fractions for the right lung cancer. At 3 mo after CIRT, the choroidal melanoma completely disappeared, as did the right lung cancer 7 mo after; the patient was in complete remission.
CONCLUSION
CIRT may be an effective treatment for double primary lung cancer and choroid melanoma.
Core Tip: Simultaneous choroidal melanoma and lung cancer are extremely rare. This report details a case of a 41-year-old woman with right-side choroidal melanoma and lung cancer treated with carbon ion radiotherapy. Seven months after treatment, the patient was in complete remission.
