Published online Nov 16, 2021. doi: 10.12998/wjcc.v9.i32.9804
Peer-review started: June 21, 2021
First decision: July 18, 2021
Revised: August 15, 2021
Accepted: September 22, 2021
Article in press: September 22, 2021
Published online: November 16, 2021
An increasing trend in colorectal cancer (CRC) occurring at younger ages has been observed worldwide, even though incidence is declining in the general popu
To investigate the prevalence, demographics, clinicopathologic features, and associated factors of young-onset CRC patients in a tertiary hospital in Indonesia.
Patients undergoing colonoscopy examination between 2008 and 2019, yielding a diagnosis of CRC were identified from medical records. The subjects were classified into two groups according to their age at diagnosis, namely early-onset (18-49 years old) and late-onset (≥ 50-years-old). Demographic data, characteristics, and risk factors of both onset age groups were evaluated using the chi-square and Fisher’s exact test.
Among 495 CRC patients confirmed by histopathology, 205 (41.4%) were cla
Early-onset CRC patients were more likely to have abdominal pain, underweight status, and HNPCC suspicion than late-onset CRC patients.
Core Tip: This is the first study to evaluate clinicodemographics of early-onset colorectal cancer (CRC) patients and associated factors in Indonesia during a 12-year period from 2008-2019. We observed a slight increase in patients with early-onset CRC during the period of 2014-2019 compared to the period of 2008-2013. A larger proportion of patients with early-onset CRC were underweight, presented with abdo