Jiang ZZ, Zheng YY, Hou CL, Liu XT. Primary mucosal-associated lymphoid tissue extranodal marginal zone lymphoma of the bladder from an imaging perspective: A case report. World J Clin Cases 2021; 9(32): 10024-10032 [PMID: 34877346 DOI: 10.12998/wjcc.v9.i32.10024]
Corresponding Author of This Article
Xia-Tian Liu, MD, Chief Doctor, Department of Ultrasound, Shaoxing People’s Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), No. 568 Zhongxing North Road, Shaoxing 312000, Zhejiang Province, China. lxt2015@126.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Nov 16, 2021; 9(32): 10024-10032 Published online Nov 16, 2021. doi: 10.12998/wjcc.v9.i32.10024
Primary mucosal-associated lymphoid tissue extranodal marginal zone lymphoma of the bladder from an imaging perspective: A case report
Zhen-Zhen Jiang, Yuan-Yuan Zheng, Chuan-Ling Hou, Xia-Tian Liu
Zhen-Zhen Jiang, Yuan-Yuan Zheng, Xia-Tian Liu, Department of Ultrasound, Shaoxing People’s Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing 312000, Zhejiang Province, China
Chuan-Ling Hou, Department of Pathology, Shaoxing People’s Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing 312000, Zhejiang Province, China
Author contributions: Jiang ZZ reviewed the literature, and contributed to manuscript drafting; Zheng YY interpreted the imaging findings; Hou CL interpreted the pathological images; Liu XT was responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Supported byShaoxing Medical Key Discipline, China, No. 2019SZD05.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xia-Tian Liu, MD, Chief Doctor, Department of Ultrasound, Shaoxing People’s Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), No. 568 Zhongxing North Road, Shaoxing 312000, Zhejiang Province, China. lxt2015@126.com
Received: July 2, 2021 Peer-review started: July 2, 2021 First decision: July 26, 2021 Revised: August 10, 2021 Accepted: September 19, 2021 Article in press: September 19, 2021 Published online: November 16, 2021 Processing time: 130 Days and 21.7 Hours
Abstract
BACKGROUND
Mucosal-associated lymphoid tissue extranodal marginal zone (MALT) lymphoma is a low-grade tumor that rarely occurs in the urinary bladder. There is currently no consensus on the common imaging findings or most appropriate treatment in MALT lymphoma in the urinary bladder due to the limited number of reports.
CASE SUMMARY
A 48-year-old woman was admitted to the hospital with a 1-year history of macroscopic hematuria. Imaging showed a large homogeneous mass with an unclear boundary and an irregular morphology in the bladder. The mass had an abundant blood supply. For further diagnosis, transurethral cystoscopic biopsy and bone marrow biopsy was performed, and the patient was finally diagnosed with primary MALT lymphoma of the bladder. R-CHOP chemotherapy was carried out. After three cycles of chemotherapy, the mass disappeared and the bladder wall thickness was only 4 mm, which indicated excellent therapeutic response to the chemotherapy. To date, the patient remains asymptomatic and she visits our hospital regularly for the completion of the remaining chemotherapy cycles.
CONCLUSION
Primary MALT lymphoma of the bladder is rare, and there are certain characteristics in the ultrasonographic findings. Imaging findings play an important role in evaluating the therapeutic efficacy and are critical during long-term follow-up after therapy.
Core Tip: Mucosal-associated lymphoid tissue extranodal marginal zone (MALT) lymphoma is a rare tumor that rarely occurs in the urinary bladder. There is no consensus on imaging findings or treatment due to the limited number of reports. We present herein, a rare case of primary bladder MALT lymphoma in a female patient from an imaging perspective. This case summarizes the imaging features of bladder MALT lymphoma and highlights the role of different imaging modalities in evaluating therapeutic efficacy and long-term follow-up after the therapy.
