Lv DN, Xu HZ, Zheng LL, Chen LL, Ling Y, Ye AQ. Extravasation of chemotherapeutic drug from an implantable intravenous infusion port in a child: A case report. World J Clin Cases 2021; 9(26): 7840-7844 [PMID: 34621835 DOI: 10.12998/wjcc.v9.i26.7840]
Corresponding Author of This Article
Hong-Zhen Xu, MD, Doctor, Department of Nursing, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, No. 3333 Binsheng Road, Binjiang District, Hangzhou 310052, Zhejiang Province, China. 6184020@zju.edu.cn
Research Domain of This Article
Pediatrics
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Dan-Ni Lv, Li-Li Zheng, Li-Li Chen, A-Qin Ye, Department of Surgical Oncology, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, Zhejiang Province, China
Hong-Zhen Xu, Yun Ling, Department of Nursing, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, Zhejiang Province, China
Author contributions: Lv DN and Xu HZ carried out the study, participated in data collection, and drafted the manuscript; Zheng LL and Chen LL performed statistical analysis and participated in study design; Ling Y and Ye AQ participated in the acquisition, analysis, and interpretation of the data, and drafted the manuscript; all authors read and approved the final manuscript.
Supported byDepartment of Education of Zhejiang Province, China, No. Y201941241.
Informed consent statement: Informed written consent was obtained from the patient’s parents for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest for this manuscript.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Zhen Xu, MD, Doctor, Department of Nursing, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, No. 3333 Binsheng Road, Binjiang District, Hangzhou 310052, Zhejiang Province, China. 6184020@zju.edu.cn
Received: March 18, 2021 Peer-review started: March 18, 2021 First decision: June 24, 2021 Revised: July 9, 2021 Accepted: July 23, 2021 Article in press: July 23, 2021 Published online: September 16, 2021 Processing time: 175 Days and 18.5 Hours
Abstract
BACKGROUND
Drug extravasation is a complication of totally implantable access port (TIAP) use and could cause tissue injury and sustained organ dysfunction. Therefore, the clinical management of children with TIAP is challenging.
CASE SUMMARY
This was a case of extravasation of a chemotherapeutic drug (paclitaxel) from an implantable infusion port in a 23-mo old child. After fully evaluating the skin at the site of extravasation, the nurse continued to use the infusion port to complete the follow-up chemotherapeutic course. The skin around the infusion port was red, and showed no ulceration, swelling, or induration at discharge.
CONCLUSION
Since children are more active and often noncompliant, it is necessary to appropriately train pediatric nurses caring for individuals with TIAPs, and any abnormal situation should be timely addressed.
Core Tip: This was a case of extravasation of a chemotherapeutic drug (paclitaxel) from an implantable infusion port in a 23-mo old child. After fully evaluating the skin at the site of extravasation, the nurse continued to use the infusion port to complete the follow-up chemotherapeutic course. The skin around the infusion port was red, and showed no ulceration, swelling, or induration at discharge.
