Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 16, 2021; 9(23): 6907-6915
Published online Aug 16, 2021. doi: 10.12998/wjcc.v9.i23.6907
Uterine tumor resembling an ovarian sex cord tumor: A case report and review of literature
Fang-Fang Zhou, Ying-Tao He, Ying Li, Min Zhang, Fang-Hong Chen
Fang-Fang Zhou, Ying-Tao He, Ying Li, Fang-Hong Chen, Department of Ultrasound, Lishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, Zhejiang Province, China
Min Zhang, Department of Pathology, Lishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, Zhejiang Province, China
Author contributions: Zhou FF was responsible for collecting the medical history of the patient and drafting the paper; He YT was responsible for collecting the medical history of the patient; Li Y was responsible for drafting the paper; Zhang M is a pathologist who provided the pathological results; Chen FH reviewed the literature and revised the manuscript; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicting interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fang-Hong Chen, BSc, Chief Doctor, Department of Ultrasound, Lishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, No. 289 Kuocang Road, Lishui 323000, Zhejiang Province, China. fanghongchen4323@163.com
Received: April 25, 2021
Peer-review started: April 25, 2021
First decision: May 24, 2021
Revised: June 2, 2021
Accepted: June 17, 2021
Article in press: June 17, 2021
Published online: August 16, 2021
Processing time: 101 Days and 24 Hours
Abstract
BACKGROUND

Endometrial stromal tumors originate from the endometrial stroma and account for < 2% of all uterine tumors. Uterine tumor resembling an ovarian sex cord tumor (UTROSCT) is a rare histological class of endometrial stromal and related tumors according to the latest World Health Organization classification of female genital tumors. Here, we report a case of UTROSCT in a 51-year-old woman.

CASE SUMMARY

A 51-year-old woman had irregular menses for 6 mo. The patient visited a local hospital for vaginal bleeding. Pelvic computed tomography (CT) showed a mass in the pelvic cavity. Five days later, she came to our hospital for further diagnosis. The results of contrast-enhanced CT and pelvic ultrasound at our hospital suggested a malignant pelvic tumor. She then underwent total removal of the uterus with bilateral salpingectomy. Postoperative histological examination showed that the tumor cells had abundant cytoplasm, ovoid and spindle-shaped nuclei, fine chromatin, a high nucleoplasm ratio, and a lamellar distribution. The findings were consistent with UTROSCT, and the results of immunohistochemical analysis supported that diagnosis. The tumor was International Federation of Gynecology and Obstetrics stage IB. No adjuvant therapy was administered after radical surgery. The patient was followed up for 58 mo, and no recurrence was found.

CONCLUSION

We report a case of UTROSCT with abnormal menstruation as a symptom, which is one of the most common symptoms. In patients with vaginal bleeding, ultrasonography can be used as a screening test because of its convenience, speed, and lack of radiation exposure. For patients with long-term tamoxifen use, routine monitoring of the endometrium is recommended. As UTROSCT may have low malignant potential, surgery remains the primary management strategy. Additionally, fertility preservation in patients of childbearing age is a vital consideration.

Keywords: Uterine tumor resembling an ovarian sex cord tumor; Endometrial stromal tumor; Pelvic; Irregular menses; Surgery; Case report

Core Tip: Uterine tumor resembling an ovarian sex cord tumor (UTROSCT) is a rare histological form of endometrial stromal and related tumors. Limited knowledge of the disease can make diagnosis difficult. Here, we present the case of a 51-year-old woman with UTROSCT.