Chen JW, Zheng LZ, Xu DH, Lin W. Extensive cutaneous metastasis of recurrent gastric cancer: A case report. World J Clin Cases 2021; 9(22): 6575-6581 [PMID: 34435028 DOI: 10.12998/wjcc.v9.i22.6575]
Corresponding Author of This Article
Wei Lin, MD, PhD, Doctor, Department of Gastrointestinal Surgery, The Affiliated Hospital of Putian University, No. 999 Dong Zhen Road, Putian 351100, Fujian Province, China. linwbj@outlook.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Aug 6, 2021; 9(22): 6575-6581 Published online Aug 6, 2021. doi: 10.12998/wjcc.v9.i22.6575
Extensive cutaneous metastasis of recurrent gastric cancer: A case report
Jun-Wei Chen, Long-Zhi Zheng, De-He Xu, Wei Lin
Jun-Wei Chen, De-He Xu, Department of Clinical Medicine, The School of Clinical Medicine, Fujian Medical University, Fuzhou 350000, Fujian Province, China
Jun-Wei Chen, De-He Xu, Department of Clinical Medicine, The Affiliated Hospital of Putian University, Putian 351100, Fujian Province, China
Long-Zhi Zheng, Wei Lin, Department of Gastrointestinal Surgery, The Affiliated Hospital of Putian University, Putian 351100, Fujian Province, China
Author contributions: Lin W designed the study; Chen JW wrote the manuscript; Xu DH, and Zheng LZ contributed to the paper design and coordination; all authors have read and approved the manuscript.
Informed consent statement: Written informed consent was obtained from the patient's parent/guardian for publication of this Case report. A copy of the written consent is available for review by the editor of this journal.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei Lin, MD, PhD, Doctor, Department of Gastrointestinal Surgery, The Affiliated Hospital of Putian University, No. 999 Dong Zhen Road, Putian 351100, Fujian Province, China. linwbj@outlook.com
Received: April 12, 2021 Peer-review started: April 12, 2021 First decision: April 27, 2021 Revised: May 17, 2021 Accepted: May 25, 2021 Article in press: May 25, 2021 Published online: August 6, 2021
Abstract
BACKGROUND
Cutaneous metastasis is a rare event associated with poor prognosis for gastric cancer and has been rarely reported in the literature.
CASE SUMMARY
A 69-year-old male patient who had undergone salvage gastrectomy and a few courses of adjuvant chemotherapy 3 mo earlier for recurrent gastric cancer developed widespread cutaneous metastases. Due to the patient’s intolerance to further adjuvant chemotherapy, he was placed in hospice care and expired 1 mo later. In the literature, gastric cancers are rarely reported as the primary malignancies for cutaneous metastasis. We, thus, provide an update on a case review published in 2014 by reviewing 10 more case reports dated from 2014 to 2020. The average age for the new group of patients was 59.4 ± 18.88-years-old. Thirty percent of the patients presented with cutaneous lesions and advanced gastric cancer synchronously while 70% developed cutaneous metastases 1.3 years to 14 years after the initial treatment for primary gastric cancer. Eighty percent of the patients received either local excision or chemo ± radiation therapy to treat their cutaneous metastases.
CONCLUSION
This report highlights cutaneous metastasis as a late and untreatable metastasis of gastric cancer.
Core Tip: Cutaneous metastasis is a rare and late metastasis associated with poor prognosis for gastric cancer. Here, we report the case of a 69-year-old male patient with recurrent advanced gastric cancer who developed extensive cutaneous metastasis. To enrich the understanding of this clinical entity, we performed an update to a case review published in 2014 by reviewing 10 more newly published case reports dating from 2014 to 2020. We found that it is important to perform thorough work-ups on patients with advanced or recurrent gastric cancer and convince the patient about the benefits of neoadjuvant chemotherapy.