Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2021; 9(22): 6575-6581
Published online Aug 6, 2021. doi: 10.12998/wjcc.v9.i22.6575
Extensive cutaneous metastasis of recurrent gastric cancer: A case report
Jun-Wei Chen, Long-Zhi Zheng, De-He Xu, Wei Lin
Jun-Wei Chen, De-He Xu, Department of Clinical Medicine, The School of Clinical Medicine, Fujian Medical University, Fuzhou 350000, Fujian Province, China
Jun-Wei Chen, De-He Xu, Department of Clinical Medicine, The Affiliated Hospital of Putian University, Putian 351100, Fujian Province, China
Long-Zhi Zheng, Wei Lin, Department of Gastrointestinal Surgery, The Affiliated Hospital of Putian University, Putian 351100, Fujian Province, China
Author contributions: Lin W designed the study; Chen JW wrote the manuscript; Xu DH, and Zheng LZ contributed to the paper design and coordination; all authors have read and approved the manuscript.
Informed consent statement: Written informed consent was obtained from the patient's parent/guardian for publication of this Case report. A copy of the written consent is available for review by the editor of this journal.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei Lin, MD, PhD, Doctor, Department of Gastrointestinal Surgery, The Affiliated Hospital of Putian University, No. 999 Dong Zhen Road, Putian 351100, Fujian Province, China. linwbj@outlook.com
Received: April 12, 2021
Peer-review started: April 12, 2021
First decision: April 27, 2021
Revised: May 17, 2021
Accepted: May 25, 2021
Article in press: May 25, 2021
Published online: August 6, 2021
Processing time: 106 Days and 16.4 Hours
Abstract
BACKGROUND

Cutaneous metastasis is a rare event associated with poor prognosis for gastric cancer and has been rarely reported in the literature.

CASE SUMMARY

A 69-year-old male patient who had undergone salvage gastrectomy and a few courses of adjuvant chemotherapy 3 mo earlier for recurrent gastric cancer developed widespread cutaneous metastases. Due to the patient’s intolerance to further adjuvant chemotherapy, he was placed in hospice care and expired 1 mo later. In the literature, gastric cancers are rarely reported as the primary malignancies for cutaneous metastasis. We, thus, provide an update on a case review published in 2014 by reviewing 10 more case reports dated from 2014 to 2020. The average age for the new group of patients was 59.4 ± 18.88-years-old. Thirty percent of the patients presented with cutaneous lesions and advanced gastric cancer synchronously while 70% developed cutaneous metastases 1.3 years to 14 years after the initial treatment for primary gastric cancer. Eighty percent of the patients received either local excision or chemo ± radiation therapy to treat their cutaneous metastases.

CONCLUSION

This report highlights cutaneous metastasis as a late and untreatable metastasis of gastric cancer.

Keywords: Cutaneous metastasis; Gastric stump cancer; Remnant gastrectomy; D2 dissection; Signet ring cell carcinoma; Case report

Core Tip: Cutaneous metastasis is a rare and late metastasis associated with poor prognosis for gastric cancer. Here, we report the case of a 69-year-old male patient with recurrent advanced gastric cancer who developed extensive cutaneous metastasis. To enrich the understanding of this clinical entity, we performed an update to a case review published in 2014 by reviewing 10 more newly published case reports dating from 2014 to 2020. We found that it is important to perform thorough work-ups on patients with advanced or recurrent gastric cancer and convince the patient about the benefits of neoadjuvant chemotherapy.