Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2021; 9(22): 6418-6427
Published online Aug 6, 2021. doi: 10.12998/wjcc.v9.i22.6418
Inflammatory myofibroblastic tumor of the pancreatic neck: A case report and review of literature
Zhi-Tao Chen, Yao-Xiang Lin, Meng-Xia Li, Ting Zhang, Da-Long Wan, Sheng-Zhang Lin
Zhi-Tao Chen, Department of Hepatobiliary and Pancreatic Surgery, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College, Hangzhou 310000, Zhejiang Province, China
Zhi-Tao Chen, Meng-Xia Li, School of Medicine, Zhejiang University, Hangzhou 310000, Zhejiang Province, China
Yao-Xiang Lin, School of Medicine, Hangzhou Normal University, Hangzhou 310003, Zhejiang Province, China
Meng-Xia Li, Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Ting Zhang, Department of Pathology, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College, Hangzhou 310000, Zhejiang Province, China
Da-Long Wan, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Sheng-Zhang Lin, Department of Hepatobiliary Surgery, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College, Hangzhou 310000, Zhejiang Province, China
Author contributions: Chen ZT and Lin SZ were the patient’s surgeons, reviewed the literature and contributed to manuscript drafting; Lin YX reviewed the literature and contributed to manuscript drafting; Li MX performed the interpretation and contributed to manuscript drafting; Zhang T analyzed and interpreted the pathologic findings; Wan DL and Lin SZ performed the disease consultation, reviewed the literature and drafted the manuscript; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sheng-Zhang Lin, MD, Chief Doctor, Department of Hepatobiliary Surgery, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College, No. 848 Dongxin Road, Hangzhou 310000, Zhejiang Province, China. wzf2lsz@163.com
Received: February 18, 2021
Peer-review started: February 18, 2021
First decision: March 11, 2021
Revised: March 23, 2021
Accepted: June 1, 2021
Article in press: June 1, 2021
Published online: August 6, 2021
Processing time: 159 Days and 20.1 Hours
Abstract
BACKGROUND

Pancreatic inflammatory myofibroblastic tumor (IMT) is a relatively rare disease that is often confused with pancreatic cancer or pancreatic neuroendocrine tumors. The histological features of IMTs show that tissue from this type of tumor contains an intermingling of fibroblast and myofibroblast proliferation, accompanied by a varying degree of inflammatory cell infiltration.

CASE SUMMARY

The management of an IMT occurring at the neck of the pancreas is presented in this paper. A 66-year-old female patient was diagnosed with a pancreatic neck mass after a series of tests. The patient underwent enucleation of the pancreatic neck tumor after a pathological diagnosis of IMT. Previous research on the clinical features, pathological diagnosis and treatment of pancreatic IMTs was reviewed. Compared with previous reports, this is a unique case of enucleation of a pancreatic IMT.

CONCLUSION

The enucleation of pancreatic IMTs may be a safe and efficient surgical method for managing such tumors with a better prognosis. Further cases are required to explore surgical measures for pancreatic IMTs.

Keywords: Inflammatory myofibroblastic tumor; Pancreatic neck; Enucleation; Case report

Core Tip: Pancreatic inflammatory myofibroblastic tumor (IMT) is a relatively rare disease that is often confused with pancreatic cancer or pancreatic neuroendocrine tumors. We present herein a 66-year-old female patient who was diagnosed with a pancreatic neck mass after a series of tests. The patient underwent enucleation of a pancreatic neck tumor after pathological diagnosis of IMT. Compared with previous reports, this is a unique case of enucleation of a pancreatic IMT. We conclude that the enucleation of pancreatic IMTs may be a safe and efficient surgical method for managing such tumors with a better prognosis.