Published online Jul 16, 2021. doi: 10.12998/wjcc.v9.i20.5637
Peer-review started: February 23, 2021
First decision: March 28, 2021
Revised: March 30, 2021
Accepted: May 20, 2021
Article in press: May 20, 2021
Published online: July 16, 2021
Primary extra-pancreatic pancreatic-type acinar cell carcinoma (ACC) is a rare malignancy, and has only been reported in the gastrointestinal tract, liver, and lymph nodes until now. Extra-pancreatic pancreatic-type ACC in the perinephric space has not been reported. Herein, we report the first case of ACC in the perinephric space and describe its clinical and imaging features, which should be considered when differentiating perinephric space neoplasms.
A 48-year-old man with a 5-year history of hypertension was incidentally found to have an asymptomatic right retroperitoneal mass during a routine health check-up. Laboratory tests were normal. Abdominal computed tomography and magnetic resonance imaging showed an oval hypervascular mass with a central scar and enhanced capsule in the right perinephric space. After surgical resection of the neoplasm, the diagnosis was primary extra-pancreatic pancreatic-type ACC. The patient was alive without recurrence or metastasis during a 15-mo follow-up.
This is the first report of an extra-pancreatic ACC in right perinephric space, which should be considered as a possible diagnosis in perinephric tumors.
Core Tip: Primary extra-pancreatic pancreatic-type acinar cell carcinoma (ACC) is a rare malignant tumor, with very few reported cases. Extra-pancreatic pancreatic-type ACC arising in the perinephric space has not been reported. The imaging characteristics of our case included an oval shape, relatively homogenous density or signal, a hypervascular pattern and rapid washout with enhancement, and an enhanced capsule. This report of diagnosis and treatment of this rare tumor. will be helpful for clinicians, radiologists and pathologists to differentiate this unusual tumor from other plausible retroperitoneal neoplasms. The recommended treatment for this tumor is complete surgical resection.