Long CY, Wang TL. Perianal superficial CD34-positive fibroblastic tumor: A case report. World J Clin Cases 2021; 9(20): 5605-5610 [PMID: 34307615 DOI: 10.12998/wjcc.v9.i20.5605]
Corresponding Author of This Article
Tao-Li Wang, MD, Doctor, Department of Pathology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, No. 116 Changjiang South Road, Zhuzhou 412007, Hunan Province, China. wtl820419@sina.cn
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 16, 2021; 9(20): 5605-5610 Published online Jul 16, 2021. doi: 10.12998/wjcc.v9.i20.5605
Perianal superficial CD34-positive fibroblastic tumor: A case report
Chen-Yan Long, Tao-Li Wang
Chen-Yan Long, The Second Department of General Surgery, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou 412007, Hunan Province, China
Tao-Li Wang, Department of Pathology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou 412007, Hunan Province, China
Author contributions: Long CY collected the data of the case and drafted the manuscript; Wang TL reviewed the manuscript and provided constructive input; both authors read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tao-Li Wang, MD, Doctor, Department of Pathology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, No. 116 Changjiang South Road, Zhuzhou 412007, Hunan Province, China. wtl820419@sina.cn
Received: February 9, 2021 Peer-review started: February 9, 2021 First decision: March 25, 2021 Revised: April 1, 2021 Accepted: May 15, 2021 Article in press: May 15, 2021 Published online: July 16, 2021 Processing time: 147 Days and 20 Hours
Abstract
BACKGROUND
Superficial CD34-positive fibroblast tumors (SCPFTs) are newly recognized fibroblast and myofibroblast tumors representing intermediate tumors. To the best of our knowledge, fewer than 50 cases have been reported. Perianal SCPFT has not been previously reported.
CASE SUMMARY
A 55-year-old man was hospitalized upon discovering a painless perianal lump 10 d prior. Physical examination showed a lump of approximately 3 cm × 4 cm in the 7 to 8 o’clock direction in the perianal area. Perianal abscess was considered the primary diagnosis. Lump removal surgery was performed under epidural anesthesia. Postoperative pathology showed a well-circumscribed, soft tissue-derived, spindle-cell tumor with strong CD34 positivity by immunohistochemistry. The final diagnosis was perianal SCPFT. There were no complications, and the patient was followed for more than 8 mo without recurrence or metastasis.
CONCLUSION
We report a case of perianal superficial CD34-positive fibroblast tumor. This rare mesenchymal neoplasm has distinctive histomorphology, which is important for diagnosis. Comprehensive consideration of clinical information, imaging, histology, and immunohistochemistry is important for diagnosis.
Core Tip: We present a new case of perianal superficial CD34-positive fibroblast tumor. Surgery is the main treatment for superficial painless slowly growing masses. Postoperative immunohistochemical examination showed that strong positivity for CD34 and good prognosis were the characteristics of the case.
