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World J Clin Cases. Jul 16, 2021; 9(20): 5420-5426
Published online Jul 16, 2021. doi: 10.12998/wjcc.v9.i20.5420
Exploration of transmission chain and prevention of the recurrence of coronavirus disease 2019 in Heilongjiang Province due to in-hospital transmission
Qi Chen, Yang Gao, Chang-Song Wang, Kai Kang, Hong Yu, Ming-Yan Zhao, Kai-Jiang Yu
Qi Chen, Chang-Song Wang, Department of Critical Care Medicine, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin 150081, Heilongjiang Province, China
Yang Gao, Department of Critical Care Medicine, The sixth Affiliated Hospital of Harbin Medical University, Harbin Medical University, Harbin 150028, Heilongjiang Province, China
Kai Kang, Ming-Yan Zhao, Kai-Jiang Yu, Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin Medical University, Harbin 150001, Heilongjiang Province, China
Hong Yu, Department of Critical Care Medicine, The Second Hospital of Harbin, Harbin 150056, Heilongjiang Province, China
Kai-Jiang Yu, Institute of Critical Care Medicine, The Sino Russian Medical Research Center of Harbin Medical University, Harbin 150081, Heilongjiang Province, China
Kai-Jiang Yu, Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin 150001, Heilongjiang Province, China
Kai-Jiang Yu, The Cell Transplantation Key Laboratory of National Health Commission, Harbin 150001, Heilongjiang Province, China
Author contributions: Chen Q, Gao Y, and Yu H participated in investigation and data collection; Gao Y and Chen Q drafted the manuscript; Chen Q, Gao Y, Wang CS, Kang K, and Zhao MY reviewed and edited the manuscript; as the corresponding author, Yu KJ had guiding roles for this work; Chen Q and Gao Y contributed equally to this work; all authors read and approved the final manuscript.
Supported by The National Natural Science Foundation of China, No. 81770276, and No. 81571871; Nn10 Program of Harbin Medical University Cancer Hospital and Scientific Research Project of Heilongjiang Health and Family Planning Commission, No. 2018086.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kai-Jiang Yu, PhD, Chief Doctor, Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin Medical University, No. 23 Youzheng Street, Nangang District, Harbin 150001, Heilongjiang Province, China. drkaijiang@163.com
Received: March 4, 2021
Peer-review started: March 4, 2021
First decision: April 14, 2021
Revised: April 25, 2021
Accepted: May 26, 2021
Article in press: May 26, 2021
Published online: July 16, 2021
Processing time: 124 Days and 11.2 Hours
Abstract

The coronavirus disease 2019 (COVID-19) epidemic is a major public health emergency characterized by fast spread, a wide range of infections, and enormous control difficulty. Since the end of December 2019, Wuhan has become the first core infection area of China's COVID-19 outbreak. Since March 2020, the domestic worst-hit areas have moved to the Heilongjiang Province due to the increased number of imported COVID-19 cases. Herein, we reported the major COVID-19 outbreak, which caused a rebound of the epidemic in Harbin, China. After the rebound, different levels of causes for the recurrence of COVID-19, including city-level, hospital-level, and medical staff-level cause, were investigated. Meanwhile, corresponding countermeasures to prevent the recurrence of the epidemic were also carried out on the city level, hospital level, and medical staff level, which eventually showed the effect of infection control function in a pandemic. In this study, we described the complete transmission chain, analyzed the causes of the outbreak, and proposed corresponding countermeasures from our practical clinical experience, which can be used as a valuable reference for COVID-19 control.

Keywords: Transmission chain; Prevention of the recurrence; COVID-19; Heilongjiang Province; In-hospital transmission

Core Tip: The coronavirus disease 2019 (COVID-19) epidemic is a major public health emergency characterized by fast spread, a wide range of infections, and enormous control difficulty. We reported the major COVID-19 outbreak, which caused a rebound of the epidemic in Harbin, China. After the rebound, different levels of causes for the recurrence of COVID-19, including city-level, hospital-level, and medical staff-level cause, were investigated. Meanwhile, corresponding countermeasures to prevent the recurrence of the epidemic were also carried out on the city level, hospital level, and medical staff level, which eventually showed the effect of infection control function in a pandemic. We described the complete transmission chain, analyzed the causes of the outbreak, and proposed corresponding countermeasures from our practical clinical experience, which can be used as a valuable reference for COVID-19 control.