Ni GH, Jiang H, Men L, Wei YY, A D, Ma X. Brugada syndrome associated with out-of-hospital cardiac arrest: A case report. World J Clin Cases 2021; 9(19): 5345-5351 [PMID: 34307588 DOI: 10.12998/wjcc.v9.i19.5345]
Corresponding Author of This Article
Xiang Ma, MD, PhD, Chief Doctor, Professor, Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, No. 8 Xinyi Road, Urumqi 830000, Xinjiang Uygur Autonomous Region, China. nghtt@163.com
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 6, 2021; 9(19): 5345-5351 Published online Jul 6, 2021. doi: 10.12998/wjcc.v9.i19.5345
Brugada syndrome associated with out-of-hospital cardiac arrest: A case report
Guo-Hua Ni, Hua Jiang, Li Men, Yuan-Yuan Wei, Dila A, Xiang Ma
Guo-Hua Ni, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Chengdu Jinjiang Sohome Comprehensive Outpatient Clinic), Chengdu 610072, Sichuan Province, China
Hua Jiang, Department of Geriatrics, Affiliated Hospital of Chengdu University, Chengdu 610081, Sichuan Province, China
Li Men, Dila A, Xiang Ma, Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, Xinjiang Uygur Autonomous Region, China
Yuan-Yuan Wei, Department of Physiology, Basic Medicine College, Chengdu University, Chengdu 610106, Sichuan Province, China
Author contributions: Ni GH, Jiang H, and Ma X conceived and designed the paper; Ni GH, Jiang H, Ma X, and Men L contributed significantly to manuscript preparation; Ni GH, Men L, Wei YY and A D performed the data collection; Ni GH and Ma X wrote the manuscript; Ni GH, Jiang H, and Ma X helped perform the analysis with constructive discussions; Ni GH, Jiang H, and Ma X reviewed and edited the manuscript; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiang Ma, MD, PhD, Chief Doctor, Professor, Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, No. 8 Xinyi Road, Urumqi 830000, Xinjiang Uygur Autonomous Region, China. nghtt@163.com
Received: March 18, 2021 Peer-review started: March 18, 2021 First decision: April 23, 2021 Revised: May 2, 2021 Accepted: May 19, 2021 Article in press: May 19, 2021 Published online: July 6, 2021 Processing time: 98 Days and 6.2 Hours
Abstract
BACKGROUND
Brugada syndrome (BrS) is an inherited disease characterized by an electrocardiogram (ECG) with a coved-type ST-segment elevation in the right precordial leads (V1-V3), which predisposes to sudden cardiac death (SCD) due to polymorphic ventricular tachycardia or ventricular fibrillation in the absence of structural heart disease. We report the case of a 29-year-old man with out-of-hospital cardiac arrest. BrS is associated with a high incidence of SCD in adults, and increasing the awareness of BrS and prompt recognition of the Brugada ECG pattern can be lifesaving.
CASE SUMMARY
A 29-year-old man suffered from out-of-hospital cardiac arrest, and after defibrillation, his ECG demonstrated a coved-type elevated ST segment in V1 and V2. These findings were compatible with type 1 Brugada pattern, and ECG of his brother showed a type 2 Brugada pattern. The diagnosis was BrS, NYHF IV, multiple organ dysfunction syndrome, sepsis, and hypoxic ischemic encephalopathy. The patient had no arrhythmia episodes after discharge throughout a follow-up period of 36 mo.
CONCLUSION
Increasing awareness of BrS and prompt recognition of the Brugada ECG pattern can be lifesaving.
Core Tip: We describe a patient with a family history of Brugada syndrome. The electrocardiograms (ECGs) of the patient and his brother showed the typical type 1 and type 2 Brugada ECG pattern, and the patient had various ECG changes in the same lead during treatment and follow-up. This case illustrates the importance of recognizing the Brugada ECG pattern and differential diagnosis for young adults associated with out-of-hospital cardiac arrest, and prompt recognition can be lifesaving.
