Chen XX, Shao SJ, Wan H. Diabetic mastopathy in an elderly woman misdiagnosed as breast cancer: A case report and review of the literature. World J Clin Cases 2021; 9(14): 3458-3465 [PMID: 34002158 DOI: 10.12998/wjcc.v9.i14.3458]
Corresponding Author of This Article
Hua Wan, MD, Chief Doctor, Director, Professor, Department of Breast, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, No. 185 Puan Street, Shanghai 200001, China. drwanhua@163.com
Research Domain of This Article
Immunology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. May 16, 2021; 9(14): 3458-3465 Published online May 16, 2021. doi: 10.12998/wjcc.v9.i14.3458
Diabetic mastopathy in an elderly woman misdiagnosed as breast cancer: A case report and review of the literature
Xiao-Xiao Chen, Shi-Jun Shao, Hua Wan
Xiao-Xiao Chen, Shi-Jun Shao, Hua Wan, Department of Breast, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200001, China
Author contributions: Chen XX consulted the literature, collected the images, and wrote this paper; Shao SJ and Wan H designed the research and revised the paper; all authors have read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient and her family for the publication of this case report and the accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hua Wan, MD, Chief Doctor, Director, Professor, Department of Breast, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, No. 185 Puan Street, Shanghai 200001, China. drwanhua@163.com
Received: December 22, 2020 Peer-review started: December 22, 2020 First decision: January 7, 2021 Revised: January 15, 2021 Accepted: February 26, 2021 Article in press: February 26, 2021 Published online: May 16, 2021 Processing time: 127 Days and 17.5 Hours
Abstract
BACKGROUND
Diabetic mastopathy is a rare benign disease in clinical practice that mainly occurs in young and middle-aged women with type 1 diabetes. It has also been reported that this disease can be found in patients with type 2 diabetes and other autoimmune diseases, such as Hashimoto's thyroiditis, as well as in men. The pathogenesis of diabetic mastopathy is not yet clear, and it is easily confused with breast cancer due to their similar clinical manifestations and imaging features.
CASE SUMMARY
A 69-year-old female patient was admitted because of painless breast masses, with a history of type 2 diabetes. The imaging and physical examination suggested a high risk of breast cancer. Further histopathological analysis showed dense lymphocytes infiltrating around the lobules of the breast, and extensive fibrosis of the surrounding stroma. Finally, diabetic mastopathy was diagnosed.
CONCLUSION
The diagnosis of diabetic mastopathy in elderly patients with painless breast masses is difficult to distinguish from breast cancer, and its imaging manifestations are not specific.
Core Tip: Diabetic mastopathy is a rare benign disease in the clinic, and its pathogenesis is not yet clear. We report a case of diabetic mastopathy in a female patient. Combined with clinical and pathological findings, we analyzed its imaging findings to better understand diabetic mastopathy and to provide a reference for the clinical diagnosis of this disease in elderly individuals.
