Pang QL, He WC, Li JX, Huang L. Symptomatic and optimal supportive care of critical COVID-19: A case report and literature review. World J Clin Cases 2020; 8(23): 6181-6189 [PMID: 33344621 DOI: 10.12998/wjcc.v8.i23.6181]
Corresponding Author of This Article
Lei Huang, MD, Chief Doctor, Department of Intensive Care Unit, Peking University Shenzhen Hospital, No. 1120 Lianhua Road, Futian District, Shenzhen 518000, Guangdong Province, China. hl0248@outlook.com
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Dec 6, 2020; 8(23): 6181-6189 Published online Dec 6, 2020. doi: 10.12998/wjcc.v8.i23.6181
Symptomatic and optimal supportive care of critical COVID-19: A case report and literature review
Qi-Lin Pang, Wen-Cheng He, Jin-Xiu Li, Lei Huang
Qi-Lin Pang, Jin-Xiu Li, Department of Intensive Care Unit, The Third People’s Hospital of Shenzhen, Shenzhen 518020, Guangdong Province, China
Wen-Cheng He, Lei Huang, Department of Intensive Care Unit, Peking University Shenzhen Hospital, Shenzhen 518000, Guangdong Province, China
Author contributions: Pang QL and Huang L collected the clinical data; Pang QL, He WC, and Huang L wrote the manuscript; Li JX and Huang L were responsible for the integrity and accuracy of the data and were the guarantors; Pang QL and He WC contributed equally to this work and should be regarded as co-first authors; all authors read and approved the final manuscript.
Supported bythe Health and Family Planning Commission of Shenzhen Municipality, No. SZLY2018024; and Sanming Project of Medicine in Shenzhen, No. SZSM201512031.
Informed consent statement: Informed written consent was obtained from the patient.
Conflict-of-interest statement: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lei Huang, MD, Chief Doctor, Department of Intensive Care Unit, Peking University Shenzhen Hospital, No. 1120 Lianhua Road, Futian District, Shenzhen 518000, Guangdong Province, China. hl0248@outlook.com
Received: August 7, 2020 Peer-review started: August 7, 2020 First decision: August 22, 2020 Revised: August 29, 2020 Accepted: September 25, 2020 Article in press: September 25, 2020 Published online: December 6, 2020 Processing time: 119 Days and 3.2 Hours
Abstract
BACKGROUND
Coronavirus disease 2019 (COVID-19) severity is classified as asymptomatic, mild, moderate, severe, and critical. Mild cases account for a large percentage of cases in the epidemic and typically exhibit a favorable prognosis. However, a 49%-67% mortality is noted in critical cases. No COVID-19-specific drug has been reported to date, and symptomatic and optimal supportive care, including oxygenation, anti-coinfection treatments, and ventilation, represent the mainstay of treatment for this disease, especially in critical patients.
CASE SUMMARY
In the above-mentioned context, we share our experience with the treatment of one critical COVID-19 case and review the relevant literature.
CONCLUSION
Timely tracheal intubation, reasonable mechanical ventilation support, appropriate anti-infection treatment, and early anticoagulation and immunity support are key factors in the successful treatment of this case.
Core Tip: The mortality of severe coronavirus disease 2019 (COVID-19) patients is high, and no effective antiviral drugs are available now. Therefore, it is important to identify a suitable treatment strategy that is associated with improved prognosis of COVID-19, especially in critically ill patients. Here, we share our experience with the treatment of one critical COVID-19 case. We conclude that timely intubation, reasonable mechanical ventilation support, appropriate anti-infection treatment, early anticoagulation and immune support, and other comprehensive measures may help to reduce the course of disease and patient mortality.
