Retrospective Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 6, 2020; 8(23): 5887-5893
Published online Dec 6, 2020. doi: 10.12998/wjcc.v8.i23.5887
Treatment of Kümmell’s disease with sequential infusion of bone cement: A retrospective study
Xing Zhang, Yong-Chao Li, Hong-Peng Liu, Bing Zhou, Hui-Lin Yang
Xing Zhang, Hui-Lin Yang, Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu Province, China
Xing Zhang, Hong-Peng Liu, Bing Zhou, Department of Orthopaedics, Gaoyou People’s Hospital Affiliated to Soochow University, Yangzhou 225600, Jiangsu Province, China
Yong-Chao Li, Department of Spinal Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China
Author contributions: Zhang X and Li YC contributed equally to this work; Li YC, Zhou B and Yang HL designed research; Zhang X performed the surgery procedure; Li YC and Liu HP analyzed data; Zhang X, Li YC and Yang HL wrote the manuscript; All authors read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Gaoyou People’s Hospital Affiliated to Soochow University.
Informed consent statement: Informed written consent was obtained from the patients for publication of this manuscript and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no financial or other conflicts of interest in relation to this research and its publication.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at spineinchina@163.com. Participants gave informed consent for data sharing.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Lin Yang, MD, PhD, Director, Doctor, Surgeon, Department of Orthopaedics, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Suzhou 215006, Jiangsu Province, China. spineinchina@163.com
Received: April 10, 2020
Peer-review started: April 10, 2020
First decision: September 24, 2020
Revised: October 6, 2020
Accepted: October 26, 2020
Article in press: October 26, 2020
Published online: December 6, 2020
Processing time: 237 Days and 19.9 Hours
Abstract
BACKGROUND

Percutaneous vertebroplasty (PVP) is an effective method for the treatment of neurologically intact Kümmell’s disease, but bone cement leakage during surgery is a problem that deserves attention.

AIM

To reduce bone cement leakage and evaluate the effect of the sequential infusion of bone cement during PVP for the treatment of stage I or II Kümmell’s disease.

METHODS

Patients with Kümmell’s disease treated in our hospital from September 2015 to September 2018 were retrospectively analyzed. Patients meeting the inclusion and exclusion criteria were divided into two groups: Traditional single infusion and sequential infusion (SI). The visual analog scale (VAS) and Oswestry disability index (ODI) were evaluated and compared, and duration of operation, bone cement content and complications were recorded.

RESULTS

Forty-five patients were included in this study; there were 24 in the traditional single infusion group and 21 in the SI group. The VAS and ODI were significantly different for both groups when compared pre- and postoperatively, whereas the differences between 1 wk postoperatively and at the final follow-up were not statistically. When the VAS and ODI of the two groups were compared, there were no significant differences at any time point. The leakage rate of bone cement was significantly lower in the SI group (14.3%, 3 of 21) than that in the traditional single infusion group (41.7%, 10 of 24).

CONCLUSION

SI in unipedicular PVP is a safe and effective procedure for neurologically intact Kümmell’s disease, and this technique could decrease the incidence of bone cement leakage.

Keywords: Kümmell’s Disease; Percutaneous vertebroplasty; Bone cement leakage; Back pain; Osteoporosis; Intravertebral vacuum cleft

Core Tip: Percutaneous vertebroplasty (PVP) is an effective method for the treatment of neurologically intact Kümmell’s disease, but bone cement leakage during surgery is a problem that deserves attention. In our study, we found that sequential infusion in unipedicular PVP is a safe and effective procedure for neurologically intact Kümmell’s disease, and this technique could decrease the incidence of bone cement leakage.