Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2020; 8(21): 5415-5419
Published online Nov 6, 2020. doi: 10.12998/wjcc.v8.i21.5415
Large and unusual presentation of gallbladder adenoma: A case report
Lin-Li Cao, Hua Shan
Lin-Li Cao, Hua Shan, Department of Medical Imaging, Jiangsu Second Hospital of Traditional Chinese Medicine, Nanjing 210017, Jiangsu Province, China
Author contributions: Shan H provided writing ideas; Cao LL collected data, analyzed them, and made constant changes; All authors read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient.
Conflict-of-interest statement: The authors of this work have nothing to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist, and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Hua Shan, MSc, Doctor, Department of Medical Imaging, Jiangsu Second Hospital of Traditional Chinese Medicine, No. 23 Nanhu Road, Nanyuan Street, Nanjing 210017, Jiangsu Province, China. shan_hua1971@163.com
Received: June 22, 2020
Peer-review started: June 22, 2020
First decision: July 24, 2020
Revised: August 5, 2020
Accepted: September 29, 2020
Article in press: September 29, 2020
Published online: November 6, 2020
Processing time: 136 Days and 19.8 Hours
Abstract
BACKGROUND

Gallbladder adenoma is a relatively rare benign tumor with a potential for malignant transformation if found to be greater than 1 cm in size.

CASE SUMMARY

Herein, we report a case of a 51-year-old female with large 3 cm × 3 cm mass of gallbladder adenoma that was misdiagnosed as adenocarcinoma due to its clinical presentation. Computed tomography and magnetic resonance imaging scans showed an irregularly shaped cauliflower-like lump in the gallbladder measuring 38 mm × 32 mm corresponding to a malignant tumor and several gallbladder stones with low diffusion-weighted imaging and equisignal of T1-weighted imaging and T2-weighted imaging; moreover, the CA 19-9 levels were very high (184.1 U/mL). Pathology reports after tumor resection showed adenoma with moderate epithelial atypia and moderate atypia in the focal area with fine pedicle and no clear infiltration.

CONCLUSION

Computed tomography and magnetic resonance imaging scans need to be carefully scrutinized in certain rare cases of adenomas with abnormal imaging features.

Keywords: Gallbladder adenoma; Computed tomography; Magnetic resonance imaging; Case report; Imaging; Misdiagnose

Core Tip: Computed tomography and magnetic resonance imaging scans showed an irregularly shaped cauliflower-like lump in the gallbladder measuring 38 mm × 32 mm corresponding to a malignant tumor and several gallbladder stones with low diffusion-weighted imaging and equisignal of T1-weighted imaging and T2-weighted imaging; moreover, the CA 19-9 levels were very high (184.1 U/mL). Pathology reports after tumor resection showed adenoma with moderate epithelial atypia and moderate atypia in the focal area with fine pedicle and no clear infiltration.