Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 26, 2020; 8(20): 4953-4957
Published online Oct 26, 2020. doi: 10.12998/wjcc.v8.i20.4953
Nasal mucosa pyoderma vegetans associated with ulcerative colitis: A case report
Shu-Xia Yu, Xian-Kui Cheng, Bin Li, Jing-Hua Hao
Shu-Xia Yu, Bin Li, Jing-Hua Hao, Department of Gastroenterology and Hepatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong Province, China
Xian-Kui Cheng, Department of Pathology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong Province, China
Author contributions: Yu SX and Cheng XK contributed to this article equally; Yu SX provided data acquisition and data analysis; Cheng XK provided the pathological reports; Li B collected the patient’s information; Xu HW took apart in the treatment of the patient; Hao JH supervised the study and was responsible for ensuring the integrity of the work from inception to published article.
Supported by Shandong Medical and Health Science and Technology Development Plan Project, No. 2018WS275.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jing-Hua Hao, MD, Chief Doctor, Department of Gastroenterology and Hepatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324 Jingwu Road, Jinan 250021, Shandong Province, China. jinghua_hao@hotmail.com
Received: May 29, 2020
Peer-review started: May 29, 2020
First decision: June 13, 2020
Revised: June 23, 2020
Accepted: September 2, 2020
Article in press: September 2, 2020
Published online: October 26, 2020
Processing time: 150 Days and 7.6 Hours
Abstract
BACKGROUND

Pyoderma vegetans (PV) is not a common extra-intestinal manifestation of ulcerative colitis (UC), while nasal mucosa PV associated with UC is particularly rare.

CASE SUMMARY

We report a 28-year-old female with a history of UC and pyoderma gangrenosum who presented with nasal pain. A nasal lesion could be observed in her nose, and histopathological examination was indicative of PV. The patient was treated with oral prednisone (40 mg per day) with good response and became symptomatically free. There was no recurrent attack after 1 year of follow-up.

CONCLUSION

Inflammatory bowel disease patients presenting with nasal pain should be further investigated to rule out the coexistence of nasal mucosa PV.

Keywords: Pyoderma vegetans; Extra-intestinal manifestations; Ulcerative colitis; Nasal lesion; Case report

Core Tip: Pyoderma vegetans (PV) is not a common extra-intestinal manifestation of ulcerative colitis (UC), while nasal mucosa PV associated with UC is particularly rare. We present herein a rare case of PV with nasal pain that evolved in a patient with ulcerative colitis. A nasal lesion could be observed in her nose and histopathological examination was indicative of PV. This case highlights that inflammatory bowel disease patients presenting with nasal pain should be further investigated to rule out the coexistence of nasal mucosa PV.