Wu ZJ, Bian TT, Zhan XH, Dong C, Wang YL, Xu WJ. Computed tomography, magnetic resonance imaging, and F-deoxyglucose positron emission computed tomography/computed tomography findings of alveolar soft part sarcoma with calcification in the thigh: A case report. World J Clin Cases 2020; 8(15): 3349-3354 [PMID: 32874992 DOI: 10.12998/wjcc.v8.i15.3349]
Corresponding Author of This Article
Wen-Jian Xu, MD, Doctor, Department of Radiology, the Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Shinan District, Qingdao 266000, Shandong Province, China. wenjianxu007@163.com
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Aug 6, 2020; 8(15): 3349-3354 Published online Aug 6, 2020. doi: 10.12998/wjcc.v8.i15.3349
Computed tomography, magnetic resonance imaging, and F-deoxyglucose positron emission computed tomography/computed tomography findings of alveolar soft part sarcoma with calcification in the thigh: A case report
Zeng-Jie Wu, Cheng Dong, Wen-Jian Xu, Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Tian-Tian Bian, Breast Disease Center, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Xiao-Hong Zhan, Department of Pathology, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Yan-Li Wang, Department of PET/CT, The Second Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Author contributions: Wu ZJ and Bian TT performed the studies, collected data, and drafted the manuscript; Zhan XH and Xu WJ performed the statistical analysis and participated in its design; Dong C and Wang YL participated in data acquisition, analysis, and interpretation and drafted the manuscript; all authors read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this case report and accompanying images.
Conflict-of-interest statement: All Authors declare that there is no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Wen-Jian Xu, MD, Doctor, Department of Radiology, the Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Shinan District, Qingdao 266000, Shandong Province, China. wenjianxu007@163.com
Received: April 10, 2020 Peer-review started: April 10, 2020 First decision: April 22, 2020 Revised: April 27, 2020 Accepted: July 16, 2020 Article in press: July 16, 2020 Published online: August 6, 2020 Processing time: 118 Days and 7.7 Hours
Abstract
BACKGROUND
Alveolar soft part sarcoma (ASPS) is an extremely rare malignant sarcoma, accounting for less than 1% of all soft-tissue sarcomas. However, limited information is available on multimodal imaging [computed tomography (CT), magnetic resonance imaging (MRI), and positron emission computed tomography/computed tomography (PET/CT)] of ASPS.
CASE SUMMARY
This study reports a case of a 35-year-old female patient with ASPS of the left thigh with lung metastasis. The patient presented with a 1-year history of a palpable mass in the lower extremity, which exhibited rapid growth for 3 wk. CT, MRI, and F-deoxyglucose PET/CT examinations were performed. CT showed a slightly hypodense or isodense mass with patchy calcifications. On MRI examination, the mass manifested hyperintensity on T1-weighted, T2-weighted, and diffusion-weighted images with some signal voids. PET/CT images demonstrated an intensely hypermetabolic mass in the left thigh and hypermetabolic nodules in lungs.
CONCLUSION
ASPS should be considered as a possible diagnosis when a slow-growing mass is detected in the soft tissue of the extremities, with hyperintensity and numerous signal voids on T1-weighted, T2-weighted, and diffusion-weighted images and intense F-deoxyglucose uptake on PET/CT. ASPS can have calcifications on CT.
Core tip: Alveolar soft part sarcoma (ASPS) is a rare malignant soft-tissue tumor with a poor prognosis. ASPS have characteristic features on magnetic resonance imaging with hyperintensity and numerous signal voids on T1-weighted and T2-weighted images and intense F-deoxyglucose uptake on positron emission computed tomography/computed tomography images. Magnetic resonance imaging combined with positron emission computed tomography/computed tomography improve the differential diagnosis of ASPS. Calcification can be found on computed tomography images.
