Wei XX, He YM, Jiang W, Li L. Ovarian endometrioid carcinoma resembling sex cord-stromal tumor: A case report. World J Clin Cases 2020; 8(12): 2623-2628 [PMID: 32607341 DOI: 10.12998/wjcc.v8.i12.2623]
Corresponding Author of This Article
Lei Li, MD, Doctor, Department of Pathology, West China Second University Hospital, Sichuan University/Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), No. 20, Section 3, Renmin South Road, Chendu 610041, Sichuan Province, China. z81uab@163.com
Research Domain of This Article
Pathology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 26, 2020; 8(12): 2623-2628 Published online Jun 26, 2020. doi: 10.12998/wjcc.v8.i12.2623
Ovarian endometrioid carcinoma resembling sex cord-stromal tumor: A case report
Xiao-Xia Wei, Yan-Mei He, Wei Jiang, Lei Li
Xiao-Xia Wei, Yan-Mei He, Wei Jiang, Lei Li, Department of Pathology, West China Second University Hospital, Sichuan University/Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Chengdu 610041, Sichuan Province, China
Author contributions: Wei XX, He YM, and Jiang W reviewed the literature; Wei XX and He YM contributed to manuscript drafting; Li L was the consulting dermatologist and analyzed and interpreted the pathology; Jiang W directed the diagnosis; and all authors approved the final version for submission.
Informed consent statement: Informed consent was obtained before any medical investigation or initiation of treatment as required and the patient agreed to publish the case.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Lei Li, MD, Doctor, Department of Pathology, West China Second University Hospital, Sichuan University/Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), No. 20, Section 3, Renmin South Road, Chendu 610041, Sichuan Province, China. z81uab@163.com
Received: February 19, 2020 Peer-review started: February 19, 2020 First decision: April 14, 2020 Revised: May 6, 2020 Accepted: May 23, 2020 Article in press: May 23, 2020 Published online: June 26, 2020 Processing time: 126 Days and 4.8 Hours
Abstract
BACKGROUND
Ovarian endometrioid carcinoma resembling sex cord-stromal tumor (ECSCSs) is rare.
CASE SUMMARY
We present a rare case of primary ECSCSs in the left ovary. A 39-year-old female patient had persistent dull pain in the lower abdomen for more than 1 mo, and she was initially diagnosed with pelvic inflammatory disease at a hospital. The patient received transabdominal hysterectomy, bilateral salpingo-oophorectomy, and pelvic and para-aortic lymph node dissection at our hospital and finally diagnosed with ECSCSs. After the operation, the patient received eight courses of cisplatinum + etoposide + bleomycin chemotherapy treatment and no evidence of tumor recurrence or metastasis was found in a 2-year follow-up period.
CONCLUSION
Ovarian endometrioid carcinoma is similar to the ovary sex cord-stromal tumor, especially when the cord-like structure is obvious. The clinical diagnosis for this tumor is difficult before surgery and pathology examination. The necessary immunohistochemical markers are of positive significance for assisting diagnosis and differential diagnosis.
Core tip: In the clinicopathological diagnosis, if ovarian tumor has the morphology of sex cord-stromal tumor, clinicians should be aware of the possibility of endometrioid carcinoma resembling sex cord-stromal tumor. Extensive and comprehensive sampling of specimens can often find focal areas of classical endometrioid carcinoma. The necessary immunohistochemical markers are of positive significance for assisting diagnosis and differential diagnosis.
