Jiang XQ, Zhang YB. Cryptococcal pneumonia in a human immunodeficiency virus-negative patient: A case report. World J Clin Cases 2020; 8(10): 2038-2043 [PMID: 32518798 DOI: 10.12998/wjcc.v8.i10.2038]
Corresponding Author of This Article
Yan-Bei Zhang, PhD, Professor, Department of Geriatric Respiratory and Critical Care, The First Affiliated Hospital of Anhui Medical University, No. 218, Jixi Road, Hefei 230022, Anhui Province, China. 371053120@qq.com
Research Domain of This Article
Respiratory System
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. May 26, 2020; 8(10): 2038-2043 Published online May 26, 2020. doi: 10.12998/wjcc.v8.i10.2038
Cryptococcal pneumonia in a human immunodeficiency virus-negative patient: A case report
Xue-Qin Jiang, Yan-Bei Zhang
Xue-Qin Jiang, Yan-Bei Zhang, Department of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Author contributions: Jiang XQ was the patient’s physician and wrote this paper; Jiang XQ and Zhang YB issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Yan-Bei Zhang, PhD, Professor, Department of Geriatric Respiratory and Critical Care, The First Affiliated Hospital of Anhui Medical University, No. 218, Jixi Road, Hefei 230022, Anhui Province, China. 371053120@qq.com
Received: January 16, 2020 Peer-review started: January 16, 2020 First decision: February 26, 2020 Revised: April 7, 2020 Accepted: April 15, 2020 Article in press: April 15, 2020 Published online: May 26, 2020
Abstract
BACKGROUND
Cases of cryptococcal pneumonia are frequently observed in patients with various innate or acquired immunodeficiencies, including organ transplant patients, cancer patients undergoing chemotherapy, patients with acquired immune deficiency syndrome, or patients on dialysis. Fluconazole is most often used to treat this condition when it is detected.
CASE SUMMARY
In the present report, we describe the case of a 42-year-old human immunodeficiency virus-negative man with normal immune function who had cryptococcal pneumonia that was diagnosed after undergoing computed tomography-guided percutaneous lung puncture. We successfully treated this patient via administration of 200 mg voriconazole twice per day for 9 mo.
CONCLUSION
This report provides evidence of the successful treatment of pulmonary cryptococcosis using voriconazole.
Core tip: In the present report, we describe the case of a 42-year-old human immunodeficiency virus-negative man with normal immune function who had cryptococcal pneumonia that was diagnosed after undergoing computed tomography-guided percutaneous lung puncture. We successfully treated this patient via administration of 200 mg voriconazole twice per day for 9 mo. This report provides evidence of the successful treatment of pulmonary cryptococcosis using voriconazole.
