Li S, Duan L, Wang FD, Lu L, Jin ZY. Carney complex: Two case reports and review of literature. World J Clin Cases 2018; 6(14): 800-806 [PMID: 30510946 DOI: 10.12998/wjcc.v6.i14.800]
Corresponding Author of This Article
Feng-Dan Wang, MD, PhD, Doctor, Department of Radiology, Peking Union Medical College Hospital, No. 1, Shuaifuyuan, Beijing 100730, China. wangfengdan@pumch.cn
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Nov 26, 2018; 6(14): 800-806 Published online Nov 26, 2018. doi: 10.12998/wjcc.v6.i14.800
Carney complex: Two case reports and review of literature
Shuang Li, Lian Duan, Feng-Dan Wang, Lin Lu, Zheng-Yu Jin
Shuang Li, Department of Radiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Shuang Li, Feng-Dan Wang, Zheng-Yu Jin, Department of Radiology, Peking Union Medical College Hospital, Beijing 100730, China
Lian Duan, Lin Lu, Department of Endocrinology, Peking Union Medical College Hospital, Beijing 100730, China
Author contributions: Duan L and Lu L designed the report; Wang FD and Jin ZY collected the patients’ clinical data; Li S wrote the paper.
Informed consent statement: Consent was obtained from the patients for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The guidelines of the CARE Checklist (2016) have been adopted.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Feng-Dan Wang, MD, PhD, Doctor, Department of Radiology, Peking Union Medical College Hospital, No. 1, Shuaifuyuan, Beijing 100730, China. wangfengdan@pumch.cn
Telephone: +86-10-69159608
Received: August 7, 2018 Peer-review started: August 7, 2018 First decision: October 3, 2018 Revised: October 16, 2018 Accepted: October 23, 2018 Article in press: October 23, 2018 Published online: November 26, 2018 Processing time: 111 Days and 18.1 Hours
Abstract
Carney complex (CNC) is an extremely rare genetic syndrome of pigmented skin lesions, endocrine hyperfunction and myxoma. Given its diverse clinical manifestations, CNC is often misdiagnosed. Recognition of some special clinical manifestations and imaging features may help with the diagnosis. Early diagnosis of CNC would alert ongoing surveillance of tumors and complications; the prognosis of CNC may thus be improved by early treatment. Herein, we report two cases of CNC with bone lesions.
Core tip: Carney complex (CNC) is a very rare disease which is often misdiagnosed because of its diverse clinical characteristics. The imaging features of bone lesions in two cases have been summarized in this paper. Recognition of some special clinical manifestations and imaging features may help with the diagnosis; the prognosis of CNC may thus be improved by early treatment.
