Chen J, Yang C, Liang CZ. Detection of a unicentric type of Castleman-like mass at the site of adrenal grand: A case report and review of literature. World J Clin Cases 2018; 6(13): 683-687 [PMID: 30430126 DOI: 10.12998/wjcc.v6.i13.683]
Corresponding Author of This Article
Chao-Zhao Liang, MD, PhD, Professor, Department of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road No. 218, Hefei 230022, Anhui Province, China. liang_chaozhao@ahmu.edu.cn
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Nov 6, 2018; 6(13): 683-687 Published online Nov 6, 2018. doi: 10.12998/wjcc.v6.i13.683
Detection of a unicentric type of Castleman-like mass at the site of adrenal grand: A case report and review of literature
Jing Chen, Cheng Yang, Chao-Zhao Liang
Jing Chen, Cheng Yang, Chao-Zhao Liang, Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Author contributions: Chen J and Yang C Contributed equally to this manuscript. Chen J drafted this manuscript; Yang C analyzed and interpreted the patient data; Liang CZ evaluated the histopathological and prepared the figures; All authors read and approved the final manuscript.
Supported by the Junior Research Project Funding of Anhui Natural Science Foundation, No. 1708085QH203; National Natural Science Founding of China, No. 81700662.
Informed consent statement: Ethical approval was obtained from the Institutional Review Boards of The First Affiliated Hospital of Anhui Medical University. Informed consent was signed by the patient for the publication of this report and related images.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Chao-Zhao Liang, MD, PhD, Professor, Department of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road No. 218, Hefei 230022, Anhui Province, China. liang_chaozhao@ahmu.edu.cn
Telephone: +86-551-63633742
Received: May 14, 2018 Peer-review started: May 14, 2018 First decision: June 8, 2018 Revised: July 26, 2018 Accepted: October 8, 2018 Article in press: October 9, 2018 Published online: November 6, 2018 Processing time: 176 Days and 23 Hours
Abstract
We present a case of adrenal CD in a 26-year-old female. The patient was referred to our hospital because of left flank pain for 1 wk. A computed tomography scan revealed a 4 cm × 3 cm well-defined mass, considered as a paraganglioma. A preoperative diagnosis of left adrenal neoplasm and urinary tract infection was made. The patient underwent anti-inflammatory therapy followed by an open operation to remove the mass in the left adrenal. Through analysis of the morphological pattern and immunohistochemical markers, a diagnosis of CD was made. During the 12-mo follow-up, there was no evidence of metastasis or recurrence. This case reminds clinicians that CD should be considered in the evaluation of an adrenal mass. Surgery is suggested for its therapeutic management.
Core tip: Castleman disease (CD), also known as giant lymph node hyperplasia or angiofollicular lymph node hyperplasia, is a highly heterogeneous clinicopathological entity belonging to the family of lymphoproliferative disorders. CD is commonly found in the mediastinum. Castleman-like masses in the adrenal grand are extraordinarily rare. We present a case of adrenal CD in a 26-year-old female. Through laparotomy, the tumor was removed. During a 12-mo follow-up, there was no evidence of metastasis or recurrence.
