Published online Nov 6, 2018. doi: 10.12998/wjcc.v6.i13.683
Peer-review started: May 14, 2018
First decision: June 8, 2018
Revised: July 26, 2018
Accepted: October 8, 2018
Article in press: October 9, 2018
Published online: November 6, 2018
Processing time: 176 Days and 23 Hours
We present a case of adrenal CD in a 26-year-old female. The patient was referred to our hospital because of left flank pain for 1 wk. A computed tomography scan revealed a 4 cm × 3 cm well-defined mass, considered as a paraganglioma. A preoperative diagnosis of left adrenal neoplasm and urinary tract infection was made. The patient underwent anti-inflammatory therapy followed by an open operation to remove the mass in the left adrenal. Through analysis of the morphological pattern and immunohistochemical markers, a diagnosis of CD was made. During the 12-mo follow-up, there was no evidence of metastasis or recurrence. This case reminds clinicians that CD should be considered in the evaluation of an adrenal mass. Surgery is suggested for its therapeutic management.
Core tip: Castleman disease (CD), also known as giant lymph node hyperplasia or angiofollicular lymph node hyperplasia, is a highly heterogeneous clinicopathological entity belonging to the family of lymphoproliferative disorders. CD is commonly found in the mediastinum. Castleman-like masses in the adrenal grand are extraordinarily rare. We present a case of adrenal CD in a 26-year-old female. Through laparotomy, the tumor was removed. During a 12-mo follow-up, there was no evidence of metastasis or recurrence.