Published online Mar 6, 2023. doi: 10.12998/wjcc.v11.i7.1513
Peer-review started: October 24, 2022
First decision: January 20, 2023
Revised: February 2, 2023
Accepted: February 15, 2023
Article in press: February 15, 2023
Published online: March 6, 2023
Multiple primary malignant neoplasms (MPMNs) are rare, while synchronous MPMNs (SMPMNs) are even less common. Owing to the progression of medical technology and the extension of life expectancy, its incidence is gradually increasing.
Although reports of breast and thyroid dual cancers are common, cases of an additional diagnosis of kidney primary cancer within the same individual are rare.
We present a case of simultaneous MPMN of three endocrine organs, reviewing the relevant literature to enhance our understanding of SMPMNs while emphasizing the increasingly important need for accurate diagnosis and multidisciplinary management whenever this challenging situation arises.
Core Tip: Multiple primary malignant neoplasms (MPMNs) are rare, while synchronous MPMNs are even less common. Owing to the progression of medical technology and the extension of life expectancy, its incidence is gradually increasing. Although reports of breast and thyroid dual cancers are common, cases of an additional diagnosis of kidney primary cancer within the same individual are rare.