Yu XL, Wu QQ, He LP, Zheng YF. Role of in vitamin D in irritable bowel syndrome. World J Clin Cases 2023; 11(12): 2677-2683 [PMID: 37214583 DOI: 10.12998/wjcc.v11.i12.2677]
Corresponding Author of This Article
Yong-Feng Zheng, MD, Doctor, Senior Researcher, Department of Anesthesiology, Affiliated People’s Hospital of Jiangsu University, No. 8 Dianli Road, Runzhou District, Zhenjiang 212002, Jiangsu Province, China. zhengyf.163@163.com
Research Domain of This Article
Endocrinology & Metabolism
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Xiao-Lan Yu, Qi-Qi Wu, Lian-Ping He, School of Medicine, Taizhou University, Jiaojiang 318000, Zhejiang Province, China
Yong-Feng Zheng, Department of Anesthesiology, Affiliated People’s Hospital of Jiangsu University, Zhenjiang 212002, Jiangsu Province, China
Author contributions: Yu XL generated the figure and wrote the first draft; Wu QQ and Zheng YF contributed to the writing and editing of the manuscript; He LP conceptualized the topic and proofread the manuscript; All authors provided supervision and approved the submission of this minireview.
Conflict-of-interest statement: All the authors report having no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong-Feng Zheng, MD, Doctor, Senior Researcher, Department of Anesthesiology, Affiliated People’s Hospital of Jiangsu University, No. 8 Dianli Road, Runzhou District, Zhenjiang 212002, Jiangsu Province, China. zhengyf.163@163.com
Received: February 17, 2023 Peer-review started: February 17, 2023 First decision: March 10, 2023 Revised: March 12, 2023 Accepted: March 24, 2023 Article in press: March 24, 2023 Published online: April 26, 2023 Processing time: 67 Days and 14.1 Hours
Abstract
Irritable bowel syndrome (IBS) is a common chronic functional gastrointestinal disorder affecting 10%-22% of adults. Its development is closely related to the gut microbiota, and the inflammatory and immune responses triggered by the gut microbiota can lead to IBS. Vitamin D (VD) effectively treats IBS with fewer side effects by improving gut microbiota, immune regulation, and anti-inflammatory effects. In the future, it is necessary to carry out epidemiological studies on the relationship between VD and IBS, clinical studies on the efficacy of supplementing VD to improve IBS, and animal studies on the mechanism of VD improving IBS. Therefore, this paper discussed the relationship between VD and IBS.
Core Tip: Irritable bowel syndrome (IBS) is a common chronic functional gastrointestinal disorder affecting 10%-22% of adults. Its development is related to the gut microbiota, and the inflammatory and immune responses triggered by the gut microbiota can lead to IBS. Vitamin D (VD) is effective in treating IBS by improving gut microbiota, immune regulation, and anti-inflammatory effects. It is necessary to carry out epidemiological studies on the relationship between VD and IBS, clinical studies on the efficacy of supplementing VD to improve IBS, and animal studies on the mechanism of VD improving IBS. This paper discussed the relationship between VD and IBS.
