Published online Apr 16, 2023. doi: 10.12998/wjcc.v11.i11.2502
Peer-review started: December 2, 2022
First decision: January 5, 2023
Revised: January 14, 2023
Accepted: March 21, 2023
Article in press: March 21, 2023
Published online: April 16, 2023
Processing time: 125 Days and 2.5 Hours
We aimed to investigate the effectiveness of endoscopic retrograde cholangiopancreatography (ERCP) for treating obstructive jaundice (OJ) post hepatoblastoma (HB) surgery (post-HB OJ) by analyzing the data of a case and performing a literature review.
Clinical data of one patient with post-HB OJ treated by ERCP were retrospectively analyzed. Furthermore, clinical characteristics and insights into the diagnosis and treatment of post-HB OJ in children were summarized via searching various databases and platforms, such as China National Knowledge Infrastructure, Wanfang database, CQVIP database, PubMed, Ringer Link, and Google Scholar. The patient reported herein underwent five chemotherapy sessions after the diagnosis of HB and right hemihepatectomy after tumor size reduction; these were followed by two postoperative chemotherapy sessions. Three months postoperatively, the patient developed icteric sclera, strong tea-colored urine, and clay-like stools, and showed signs of skin itchiness; blood analysis showed significantly an increased conjugated bilirubin (CB) level (200.3 μmol/L). Following the poor efficacy of anti-jaundice and hepatoprotective treatments, the patient underwent ERCP. Intraoperative imaging showed a dilated bile duct in the porta hepatis with significant distal stenosis. A 5 Fr nasopancreatic tube was placed in the dilated area through the stricture for external drainage, and the patient was extubated on postoperative day 6. Postoperatively, the patient’s stool turned yellow, and the CB level decreased to 78.2 μmol/L. Fifteen days later, ERCP was repeated due to unrelieved jaundice symptoms, wherein a 7 Fr naso
Post-HB OJ is rare. Compared to biliary tract reconstruction, ERCP is less invasive and has a better therapeutic effect.
Core Tip: This study aimed to investigate the effectiveness of endoscopic retrograde cholangiopancreatography (ERCP) in the treatment of obstructive jaundice following hepatoblastoma surgery by analyzing the data of a case and performing a literature review. We found that ERCP is less invasive and has a better therapeutic effect compared to biliary tract reconstruction.