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World J Clin Cases. Apr 6, 2023; 11(10): 2160-2167
Published online Apr 6, 2023. doi: 10.12998/wjcc.v11.i10.2160
Treatment of stellate ganglion block in diseases: Its role and application prospect
Jing-Jing Deng, Cai-Ling Zhang, Dian-Wen Liu, Tao Huang, Jian Xu, Qing-Yan Liu, Yue-Nong Zhang
Jing-Jing Deng, Jian Xu, Qing-Yan Liu, Yue-Nong Zhang, Department of Surgery and Anesthesia, The Third Affiliated Hospital of Sun Yat-sen University Yuedong Hospital, Meizhou 514700, Guangdong Province, China
Cai-Ling Zhang, Department of Anesthesiology, Meizhou Hospital of Traditional Chinese Medicine, Meizhou 514700, Guangdong Province, China
Dian-Wen Liu, Department of Anesthesiology, Shangqiu Maternal and Children Health Care Hospital, Shangqiu 476000, Henan Province, China
Tao Huang, Department of Anesthesiology, Fengshun Hospital of Traditional Chinese Medicine, Meizhou 514700, Guangdong Province, China
Author contributions: Deng JJ and Zhang CL composed the manuscript; Liu DW and Huang T collected and sorted out the literature; Xu J and Liu QY edited and polished the manuscript; Zhang YN designed the outline and edited the manuscript; All authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yue-Nong Zhang, MD, Chief Doctor, Doctor, Department of Surgery and Anesthesia, The Third Affiliated Hospital of Sun Yat-sen University Yuedong Hospital, No. 124 Park North Road, Xinxian Town, Meizhou, 514700, Guangdong Province, China. 36856665@qq.com
Received: November 14, 2022
Peer-review started: November 14, 2022
First decision: February 17, 2023
Revised: February 24, 2023
Accepted: March 14, 2023
Article in press: March 14, 2023
Published online: April 6, 2023
Processing time: 136 Days and 1.1 Hours
Abstract

The stellate ganglion (SG), as a type of sympathetic ganglion, consists of the sixth and seventh cervical vertebrae and the first thoracic sympathetic ganglia. SG block (SGB) is a minimally invasive injection that aims to inject low-concentration local anesthetics to induce a broad sympathetic blocking effect near the SG. There have been no changes and progress in the clinical application of SGB since the 1830s due to several potential risks, including hematoma from blood vessel injury, hoarseness from recurrent laryngeal nerve injury, and cardiopulmonary arrest. The feasibility and safety of SGB have greatly improved since the appearance of ultrasound-guided SGB. In recent years, SGB has been widely applied in the field of non-anesthesiology sedation, with significant therapeutic effects on pain, immunological diseases, somnipathy, psychological disorders, arrhythmias, and endocrine diseases. The present study reviews the present application of SGB in clinical practice.

Keywords: Echocardiography; Pain; Immunological diseases; Somnipathy; Psychological disorders; Arrhythmias; Endocrine diseases

Core Tip: Several reviews in the literature have contributed to the therapeutic effect of stellate ganglion block (SGB). The present study reviews the anatomical structure and mechanism of SGB, the advantages of ultrasound localization, and the application of SGB in the treatment of painful diseases, immunological diseases, somnipathy, psychological diseases, arrhythmias, and endocrine diseases.