Guo XW, Jia XD, Ji AD, Zhang DQ, Jia DZ, Zhang Q, Shao Q, Liu Y. Large cystic-solid pulmonary hamartoma: A case report. World J Clin Cases 2022; 10(8): 2650-2656 [PMID: 35434052 DOI: 10.12998/wjcc.v10.i8.2650]
Corresponding Author of This Article
Xiao-Wan Guo, MD, Doctor, Department of Radiology, Hebei General Hospital, No. 348 Hepingxi Road, Shijiazhuang 050000, Hebei Province, China. angelguoxiaowan@163.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Mar 16, 2022; 10(8): 2650-2656 Published online Mar 16, 2022. doi: 10.12998/wjcc.v10.i8.2650
Large cystic-solid pulmonary hamartoma: A case report
Xiao-Wan Guo, Xu-Dong Jia, A-Dan Ji, Dan-Qing Zhang, De-Zhao Jia, Qi Zhang, Qiu Shao, Yang Liu
Xiao-Wan Guo, Dan-Qing Zhang, De-Zhao Jia, Qi Zhang, Qiu Shao, Department of Radiology, Hebei General Hospital, Shijiazhuang 050000, Hebei Province, China
Xu-Dong Jia, Departments of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang 050005, Hebei Province, China
A-Dan Ji, Department of Medical Record Statistics, Hebei General Hospital, Shijiazhuang 050000, Hebei Province, China
Yang Liu, Department of Pathology, Hebei General Hospital, Shijiazhuang 050000, Hebei Province, China
Author contributions: Guo XW reviewed the literature and contributed to manuscript drafting; Jia XD performed image software processing and edited the manuscript; Ji AD and Liu Y performed image software processing; Zhang DQ, Jia DZ, Zhang Q, and Shao Q contributed to data curation.
Informed consent statement: Informed written consent was obtained from the patients for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Wan Guo, MD, Doctor, Department of Radiology, Hebei General Hospital, No. 348 Hepingxi Road, Shijiazhuang 050000, Hebei Province, China. angelguoxiaowan@163.com
Received: November 4, 2021 Peer-review started: November 4, 2021 First decision: December 27, 2021 Revised: January 4, 2022 Accepted: February 10, 2022 Article in press: February 10, 2022 Published online: March 16, 2022 Processing time: 126 Days and 11.2 Hours
Abstract
BACKGROUND
It now seems that all pulmonary hamartomas (PHs) are large cystic-solid lesions that are difficult to diagnose. However, few cases of large cystic-solid PHs have been reported. The present case report presents a large cystic-solid PH and provides a literature review of the imaging features, formation mechanism and histopathological basis of PHs.
CASE SUMMARY
A 53-year-old woman with no clinical symptoms underwent a chest computed tomography (CT) examination at our hospital. Nonenhanced CT images revealed a large, flat tumor with multiple air-containing cysts in the left thoracic cavity and a cystic part confined to the medial side of the tumor; the solid part of the tumor showed abundant fat and lamellar soft tissue components. Multiple small blood vessels were detected in the solid part of the tumor on contrast-enhanced CT images. Given the large size of the lesion, the patient elected to undergo surgery. Histological examination revealed PH. A detailed review of the patient’s CT imaging showed that the lesion had a small vascular pedicle to the left lower lobe, which was a clue to its lung tissue histological origin. According to immunohistochemical staining, the confined multiple air-containing cysts were caused by the entrapment of respiratory/alveolar epithelium.
CONCLUSION
This case shows the imaging manifestations of a large PH. Heightened awareness of its formation mechanism and histopathological basis may alert radiologists to consider this diagnosis in their daily workflow.
Core Tip: We describe a large pulmonary hamartoma (PH) and its preoperative computed tomography (CT) imaging features, including multiple air-containing cysts, a rich blood supply and a vascular pedicle. The CT imaging features, formation mechanism, and histopathological basis of a large PH are summarized in this case report.
