Ding YZ, Tang DQ, Zhao XJ. Mantle cell lymphoma with endobronchial involvement: A case report. World J Clin Cases 2022; 10(8): 2604-2609 [PMID: 35434069 DOI: 10.12998/wjcc.v10.i8.2604]
Corresponding Author of This Article
Xiao-Jing Zhao, PhD, Chief Doctor, Department of Thoracic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pujian Road, Shanghai 200127, China. 18133@renji.com
Research Domain of This Article
Respiratory System
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Mar 16, 2022; 10(8): 2604-2609 Published online Mar 16, 2022. doi: 10.12998/wjcc.v10.i8.2604
Mantle cell lymphoma with endobronchial involvement: A case report
Yi-Zong Ding, Dao-Qiang Tang, Xiao-Jing Zhao
Yi-Zong Ding, Xiao-Jing Zhao, Department of Thoracic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
Dao-Qiang Tang, Department of Pathology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
Author contributions: Ding YZ collected the clinical data and wrote the manuscript; Tang DQ analyzed the clinical data; and Zhao XJ designed the work; all authors read and approved the final manuscript.
Informed consent statement: A written informed consent was obtained from the patient included in this case report.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: We have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Jing Zhao, PhD, Chief Doctor, Department of Thoracic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pujian Road, Shanghai 200127, China. 18133@renji.com
Received: October 2, 2021 Peer-review started: October 2, 2021 First decision: December 10, 2021 Revised: December 14, 2021 Accepted: February 10, 2022 Article in press: February 10, 2022 Published online: March 16, 2022
Abstract
BACKGROUND
Mantle cell lymphoma (MCL) is a subtype of Non-Hodgkin's lymphoma (NHL). MCL frequently affects extranodal sites while endobronchial involvement is uncommon. Only 5 cases of MCL with endobronchial involvement have been previously reported.
CASE SUMMARY
A 56-year-old male patient arrived at the hospital complaining of a dry cough. A mass in the right upper lobe of the lung was revealed in Chest computed tomography (CT). Right lung hilar and mediastinal lymphadenopathies were also found by CT scan. The patient was diagnosed with central-type lung cancer with multiple lymph node metastases after positron emission tomography (PET) CT scan examination. The fiber optic bronchoscope examination revealed diffuse neoplasm infiltration in the inlet of the right up lobar bronchus. The patient was finally diagnosed with MCL based on the bronchoscopy and mediastinoscopy biopsy results.
CONCLUSION
MCL could masquerade as central type lung cancer. An endobronchial biopsy examination is necessary for the early diagnosis of MCL.
Core Tip: We reported a case of mantle cell lymphoma (MCL) with endobronchial involvement. MCL with endobronchial involvement is very rare. Only five such cases have been previously reported. Positron emission tomography - computed tomography is recommended for differential diagnosis and detection of extranodal sites of MCL. A pathological diagnosis can be made based on an endobronchial biopsy by bronchoscopy but doctors should prompt efforts to establish enough tissues.
