Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2022; 10(35): 13081-13087
Published online Dec 16, 2022. doi: 10.12998/wjcc.v10.i35.13081
Hammered silver appearance of the corneal endothelium in Fuchs uveitis syndrome: A case report
Yan-Yan Cheng, Cong-Ying Wang, Yan-Fang Zheng, Ming-Yu Ren
Yan-Yan Cheng, Cong-Ying Wang, Yan-Fang Zheng, Ming-Yu Ren, Department of Glaucoma, Hebei Eye Hospital, Xingtai 054000, Hebei Province, China
Yan-Yan Cheng, Cong-Ying Wang, Yan-Fang Zheng, Ming-Yu Ren, Department of Glaucoma, Hebei Provincial Key Laboratory of Ophthalmology, Xingtai 054000, Hebei Province, China
Yan-Yan Cheng, Cong-Ying Wang, Yan-Fang Zheng, Ming-Yu Ren, Department of Glaucoma, Hebei Provincial Clinical Research Center for Eye Diseases, Xingtai 054000, Hebei Province, China
Author contributions: Cheng YY and Ren MY conceptualized and designed the study and drafted the initial manuscript; Wang CY and Zheng YF collected the data and carried out the initial analyses; Cheng YY and Ren MY reviewed and revised the manuscript; and all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ming-Yu Ren, MMed, Chief Physician, Department of Glaucoma, Hebei Eye Hospital, No. 399 Quanbeidong, Xingtai 054000, Hebei Province, China. 147237583@qq.com
Received: September 24, 2022
Peer-review started: September 24, 2022
First decision: October 24, 2022
Revised: October 26, 2022
Accepted: November 14, 2022
Article in press: November 14, 2022
Published online: December 16, 2022
Processing time: 80 Days and 17.9 Hours
Abstract
BACKGROUND

Hammered silver appearance of the corneal endothelium is considered a characteristic change in iridocorneal-endothelial syndrome. Herein we report an interesting case of hammered silver appearance of the corneal endothelium in Fuchs uveitis syndrome (FUS).

CASE SUMMARY

A 49-year-old man with progressive vision loss in the right eye for one year was admitted to our hospital. The clinical manifestations of the patient’s right eye were mild conjunctival hyperemia, scattered stellate keratic precipitates on the corneal endothelium, normal depth anterior chamber, 2+ cellular reaction in the aqueous humor, diffuse iris depigmentation, absence of synechia, Koeppe nodules, opalescent lens, and vitreous opacity. FUS and a complicated cataract were diagnosed based on the typical clinical manifestations. The corneal endothelial changes were recorded in detail by slit-lamp examination, specular microscopy, and in vivo confocal microscopy before cataract extraction, revealing a hammered silver appearance of the corneal endothelium in the affected eye, a wide-band dark area, as well as irregular corneal endothelial protuberances and dark bodies of various sizes. Subsequently, the patient underwent phacoemulsification combined with intraocular lens implantation, and his postoperative visual acuity recovered to 1.0.

CONCLUSION

Hammered silver appearance of the corneal endothelium in FUS, which is considered a more serious manifestation of endothelial damage, is rare and may be caused by many irregular protrusions in the corneal endothelium.

Keywords: Fuchs uveitis syndrome; Corneal endothelium; Hammered silver; Case report

Core Tip: A 49-year-old man was diagnosed with Fuchs uveitis syndrome (FUS) and a complicated cataract based on typical clinical manifestations. Slit-lamp examination, specular microscopy, in vivo confocal microscopy revealed a hammered silver appearance of the corneal endothelium in the affected eye, a wide-band dark area, as well as irregular corneal endothelial protuberances and dark bodies of various sizes. Subsequently, the patient underwent phacoemulsification combined with intraocular lens implantation. Hammered silver appearance of the corneal endothelium in FUS, which is considered a more serious manifestation of endothelial damage, is rare and may be caused by many irregular protrusions in the corneal endothelium.