Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 16, 2022; 10(32): 11853-11860
Published online Nov 16, 2022. doi: 10.12998/wjcc.v10.i32.11853
Laparoscopic treatment of inflammatory myofibroblastic tumor in liver: A case report
Yang-Yang Li, Jin-Feng Zang, Chi Zhang
Yang-Yang Li, Jin-Feng Zang, Chi Zhang, Department of Hepatobiliary Surgery, Taizhou People’s Hospital, The Fifth Affiliated Hospital of Medical School of Nantong University, Taizhou 225300, Jiangsu Province, China
Author contributions: Li YY collected and collated the data, performed the laparoscopic procedures and wrote the manuscript; Zang JF and Zhang C designed and performed the laparoscopic procedures; all authors read and approved the final manuscript, and gave their approval to the submitted version.
Informed consent statement: Informed written consent was obtained from the patients for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin-Feng Zang, MD, Chief Physician, Department of Hepatobiliary Surgery, Taizhou People’s Hospital, The Fifth Affiliated Hospital of Medical School of Nantong University, No. 366 Taihu Road, Taizhou 225300, Jiangsu Province, China. xkfy1979@126.com
Received: May 11, 2022
Peer-review started: May 11, 2022
First decision: June 27, 2022
Revised: July 12, 2022
Accepted: August 30, 2022
Article in press: August 30, 2022
Published online: November 16, 2022
Abstract
BACKGROUND

Inflammatory myofibroblastic tumor in the liver (IMTL) is a rare borderline mesenchymal tumor. Neither clinical symptoms nor laboratory tests have absolute specificity for the diagnosis of IMTL, and imaging also lacks obvious specificity. Although there are sporadic reports of recurrence after surgical treatment, surgical resection is the mainstay of treatment.

CASE SUMMARY

A 29-year-old man complained of general weakness, slight discomfort in the upper abdomen, with a history of upper respiratory tract infection for 1 wk before admission. Plain and enhanced upper abdominal magnetic resonance imaging showed a mass in liver segments II and III (48 mm × 53 mm). He was treated by laparoscopic left lateral segmentectomy. Postoperative pathological examination with hematoxylin and eosin staining suggested that the mass in liver segments II and III was IMTL. During 21 mo postoperative follow-up, no obvious residual or recurrent lesions were observed.

CONCLUSION

There is a risk of malignant degeneration in IMTL. The principal choice of treatment is laparoscopic left lateral segmentectomy.

Keywords: Inflammatory myofibroblastic tumor, Hepatectomy, Laparoscopy, Liver, Case report

Core tip: Inflammatory myofibroblastic tumor (IMT) is a rare borderline mesenchymal tumor with myofibroblastic proliferation and varying number of inflammatory cells that can occur in the lungs, stomach, intestines, gallbladder and nervous system. We present a rare case of IMT in the liver (IMTL) and its treatment with laparoscopic left lateral segmentectomy. This was a rare case of IMTL that was difficult to diagnose and treat, which was unresponsive to pharmacological treatment. This case highlights the importance of surgery for IMTL located in segments II and III. Laparoscopic treatment of IMTL is effective and minimally invasive.