Dai SJ, Yu QJ, Zhu XY, Shang QZ, Qu JB, Ai QL. Autoimmune encephalitis with posterior reversible encephalopathy syndrome: A case report. World J Clin Cases 2022; 10(30): 11044-11048 [PMID: 36338200 DOI: 10.12998/wjcc.v10.i30.11044]
Corresponding Author of This Article
Qiu-Jian Yu, MD, PhD, Doctor, Department of Neurology, First Affiliated Hospital of Kunming Medical University, No 295 Xichang Road, Xishan District, Kunming 650000, Yunnan Province, China. q.yu4@foxmail.com
Research Domain of This Article
Neuroimaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Shu-Juan Dai, Qiu-Jian Yu, Xiao-Yan Zhu, Qun-Zhu Shang, Qing-Long Ai, Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming 650000, Yunnan Province, China
Ji-Bo Qu, Department of Neurology, Hospital of Honghe State Affiliated to Kunming Medical University, Honghe 661000, Yunnan Province, China
Author contributions: All authors contributed to the article, critically revised the manuscript and approved the submitted version.
Supported byNational Natural Science Foundation of China, No. 8216050484.
Informed consent statement: The study participant's legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qiu-Jian Yu, MD, PhD, Doctor, Department of Neurology, First Affiliated Hospital of Kunming Medical University, No 295 Xichang Road, Xishan District, Kunming 650000, Yunnan Province, China. q.yu4@foxmail.com
Received: May 6, 2022 Peer-review started: May 6, 2022 First decision: July 29, 2022 Revised: August 9, 2022 Accepted: September 23, 2022 Article in press: September 23, 2022 Published online: October 26, 2022 Processing time: 167 Days and 20.3 Hours
Abstract
BACKGROUND
Posterior reversible encephalopathy syndrome (PRES) is a neuroimaging-based syndrome and is associated with multifocal vasogenic cerebral edema. Patients with PRES frequently demonstrate headache, seizure, encephalopathy, altered mental function, visual loss and so on. We here report a patient who showed persistent neurologic deficits after PRES and was ultimately diagnosed with autoimmune encephalitis (AE).
CASE SUMMARY
This case exhibits a rare imaging manifestation of anti-casper 2 encephalitis which was initially well-matched with PRES and associated vasogenic edema.
CONCLUSION
AE should be further considered when the etiology, clinical manifestations, and course of PRES are atypical.
Core Tip: Posterior reversible encephalopathy syndrome (PRES) is associated with many diverse clinical comorbid, the most common of which are hypertension, eclampsia, renal failure and immunosuppressive treatment. PRES is a neuroimaging-based syndrome and is associated with multifocal vasogenic cerebral edema. Patients with PRES are frequently manifested by headache, seizure, encephalopathy, altered mental function, visual loss, etc. We here report a patient who showed persistent neurologic deficits after PRES and was ultimately diagnosed with autoimmune encephalitis.
