Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 26, 2022; 10(15): 5082-5087
Published online May 26, 2022. doi: 10.12998/wjcc.v10.i15.5082
Catheter-related infections caused by Mycobacterium abscessus in a patient with motor neurone disease: A case report
Su-Fei Pan, Yuan-Yuan Zhang, Xiao-Zhen Wang, Jing-Jing Sun, Shao-Ling Song, Yu-Rong Tang, Ji-Liang Wang
Su-Fei Pan, Yuan-Yuan Zhang, Xiao-Zhen Wang, Jing-Jing Sun, Shao-Ling Song, Yu-Rong Tang, Ji-Liang Wang, Department of Laboratory Medicine, Shengli Oilfield Central Hospital, Dongying 257034, Shandong Province, China
Author contributions: Pan SF, Zhang YY, and Wang JL designed the research and wrote the paper; Pan SF, Zhang YY, Wang XZ, Sun JJ, Song SL, and Tang YR collected all the data related to the case report; Wang JL supervised the report; all authors have read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ji-Liang Wang, MS, Chief Doctor, Department of Laboratory Medicine, Shengli Oilfield Central Hospital, No. 31 Jinan Road, Dongying District, Dongying 257034, Shandong Province, China. zxyywjl@163.com
Received: December 16, 2021
Peer-review started: December 16, 2021
First decision: February 14, 2022
Revised: February 23, 2022
Accepted: March 26, 2022
Article in press: March 26, 2022
Published online: May 26, 2022
Processing time: 159 Days and 7.1 Hours
Abstract
BACKGROUND

Mycobacterium abscessus (M. abscessus) is a rapidly growing mycobacterium and ubiquitous in the environment, which infrequently causes disease in humans. However, it can cause cutaneous or respiratory infections among immunocompromised hosts. Due to the resistance to most antibiotics, the pathogen is formidable and difficult-to-treat.

CASE SUMMARY

Here, we present a case of catheter-related M. abscessus infections in a patient with motor neurone disease. Catheter and peripheral blood cultures of the patient showed positive results during Gram staining and acid-fast staining. The alarm time of catheter blood culture was 10.6 h earlier than that of peripheral blood. After removal of the peripherally inserted central catheter, secretion and catheter blood culture were positive. M. abscessus was identified by matrix-assisted laser desorption ionization-time of flight mass spectrometry and 16S rDNA sequencing.

CONCLUSION

For catheter-related M. abscessus infection, rapid diagnosis and timely and adequate antimicrobial therapy are crucial.

Keywords: Catheter-related infections; Diagnosis; Motor neurone disease; Mycobacterium abscessus; Case report

Core Tip: Mycobacterium abscessus (M. abscessus) is a rapidly growing mycobacterium and ubiquitous in the environment, which infrequently causes disease in humans. However, it can cause cutaneous or respiratory infections among immunocompromised hosts. Due to the resistance to most antibiotics, the pathogen is formidable and difficult-to-treat. Here, we present a case of catheter-related M. abscessus infections in a patient with motor neurone disease. M. abscessus was identified by matrix-assisted laser desorption ionization-time of flight mass spectrometry and 16S rDNA sequencing. For catheter-related M. abscessus infection, rapid diagnosis and timely and adequate antimicrobial therapy are crucial.