Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 26, 2022; 10(15): 4957-4963
Published online May 26, 2022. doi: 10.12998/wjcc.v10.i15.4957
Total femur replacement with 18 years of follow-up: A case report
Yi-Hao Yang, Jia-Xiang Chen, Qiu-Yun Chen, Yu Wang, Yao-Bin Zhou, Hong-Wei Wang, Tao Yuan, Hong-Pu Sun, Lin Xie, Zhi-Hong Yao, Zuo-Zhang Yang
Yi-Hao Yang, Jia-Xiang Chen, Qiu-Yun Chen, Yu Wang, Tao Yuan, Hong-Pu Sun, Zhi-Hong Yao, Zuo-Zhang Yang, Department of Orthopaedics, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Yunnan Cancer Center, Kunming 650118, Yunnan Province, China
Yao-Bin Zhou, Hong-Wei Wang, Department of Orthopaedics, The People’s Hospital of Fuyuan, Fuyuan County, Qujing 655500, Yunnan Province, China
Lin Xie, Department of Medical Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Yunnan Cancer Center, Kunming 650118, Yunnan Province, China
Author contributions: Yang YH collected the data of case, reviewed the literatures and drafted the manuscripts; Chen JX and Chen QY help to collect the data of the case; Yang ZZ, Yuan T, and Sun HP carried out the operation and revised the manuscript; Xie L and Yao ZH reviewed the literatures and revised the manuscript; Wang Y, Zhou YB and Wang HW were collecting medical images; all authors read and approved the final manuscript; Yang YH, Chen JX, Chen QY, Wang Y, Zhou YB, and Wang HW are co-first authors.
Supported by National Natural Science Foundation of China, No. 81972764, and No. 81960488; the Joint Special Funds for the Department of Science and Technology of Yunnan Province-Kunming Medical University, No. 2018FE001-060 , and No. 2019FE001-152; Scientific Research Projects of Internal Research Institutions of Medical and Health Units in Yunnan Province, No. 2017NS196, No. 2017NS197, and No. 2018NS069.
Informed consent statement: The patient and the families were informed that related data and attached images in the case would be submitted for publication. Since they had signed the Informed Consent Form.
Conflict-of-interest statement: The authors declare that they have no conflicts of interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zuo-Zhang Yang, MD, Professor, Department of Orthopaedics, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Yunnan Cancer Center, No 519 Kunzhou Road, Xishan District, Kunming 650118, Yunnan Province, China. yangzuozhang@163.com
Received: October 17, 2021
Peer-review started: October 17, 2021
First decision: December 17, 2021
Revised: December 27, 2021
Accepted: April 9, 2022
Article in press: April 9, 2022
Published online: May 26, 2022
Abstract
BACKGROUND

Osteosarcoma is one of the most common primary malignant bone tumors and is more common in adolescents. The femur is the most common site of osteosarcoma, and many patients require total femur replacement. We reviewed the relevant literature and case findings, summarized and analyzed this case in combination with relevant literature, and in doing so improved the understanding of the technology.

CASE SUMMARY

The case we report was a 15-year-old patient who was admitted to the hospital 15 days after the discovery of a right thigh mass. The diagnosis was osteosarcoma of the right femoral shaft. After completion of neoadjuvant chemotherapy and preoperative preparation, total right femoral resection + artificial total femoral replacement was performed. Then, chemotherapy was continued after surgery. The patient recovered well after treatment, and the function of the affected limb was good. No recurrence, metastasis, prosthesis loosening, dislocation, fracture or other complications were found during 18 years of follow-up. At present, the patient can still work and lives normally. The results of the medium- and long-term follow-up were satisfactory.

CONCLUSION

Artificial total femur replacement is a feasible limb salvage operation for patients with femoral malignant tumors, and the results of medium- and long-term follow-up are satisfactory.

Keywords: Total femur replacement, Osteosarcoma, Medium and long-term follow-up, Case report

Core Tip: Artificial total femur replacement is a feasible limb salvage operation for patients with femoral malignant tumors, and the results of medium- and long-term follow-up are satisfactory.