Yang YZ, Hu WX, Zhai HJ. Special type of Wernekink syndrome in midbrain infarction: Four case reports. World J Clin Cases 2022; 10(15): 4935-4941 [PMID: 35801050 DOI: 10.12998/wjcc.v10.i15.4935]
Corresponding Author of This Article
Hong-Jiang Zhai, MD, Associate Chief Physician, Department of Neurology, Lu'an Hospital Affiliated to Anhui Medical University (People’s Hospital of Lu’an City), No. 21 Wanxi West Road, Lu'an 237005, Anhui Province, China. hjzhai_dr@163.com
Research Domain of This Article
Neuroimaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. May 26, 2022; 10(15): 4935-4941 Published online May 26, 2022. doi: 10.12998/wjcc.v10.i15.4935
Special type of Wernekink syndrome in midbrain infarction: Four case reports
Yun-Zhou Yang, Wen-Xia Hu, Hong-Jiang Zhai
Yun-Zhou Yang, Wen-Xia Hu, Hong-Jiang Zhai, Department of Neurology, Lu'an Hospital Affiliated to Anhui Medical University (People’s Hospital of Lu’an City), Lu'an 237005, Anhui Province, China
Author contributions: Yang YZ and Hu WX reviewed the literature and contributed to manuscript drafting; Zhai HJ analyzed and interpreted the imaging findings; Yang YZ and Hu WX reviewed the literature and drafted the manuscript; Yang YZ and Zhai HJ were responsible for the revision of the manuscript for important intellectual content; All authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Jiang Zhai, MD, Associate Chief Physician, Department of Neurology, Lu'an Hospital Affiliated to Anhui Medical University (People’s Hospital of Lu’an City), No. 21 Wanxi West Road, Lu'an 237005, Anhui Province, China. hjzhai_dr@163.com
Received: September 27, 2021 Peer-review started: September 27, 2021 First decision: January 11, 2022 Revised: February 21, 2022 Accepted: April 3, 2022 Article in press: April 3, 2022 Published online: May 26, 2022 Processing time: 239 Days and 12.9 Hours
Abstract
BACKGROUND
Wernekink commissural syndrome (WCS) is a distinct midbrain syndrome that involves the caudal tegmentum of the midbrain and selectively damages the Wernekink commissure involved in the decussation of the superior cerebellar peduncle in midbrain. The aim of the study was to explore the clinical manifestations, imaging characteristics, and differential diagnosis of WCS in midbrain infarction to provide reference for clinicians in the diagnosis of WCS.
CASE SUMMARY
The clinical data of 4 patients with WCS with midbrain infarction were analyzed retrospectively. WCS is a rare syndrome that can be diagnosed based on its characteristic symptoms and imaging findings of magnetic resonance imaging.
CONCLUSION
Clinicians should look for this syndrome in cases of bilateral cerebellar dysfunction and eye movement disorders.
Core Tip: The aim of the study was to explore the clinical manifestations, imaging characteristics, and differential diagnosis of Wernekink commissural syndrome (WCS) in midbrain infarction and to provide reference for the clinicians in the diagnosis of WCS. WCS is a rare syndrome that can be diagnosed based on its characteristic symptoms and imaging findings of magnetic resonance imaging. Clinicians should look for this syndrome in cases of bilateral cerebellar dysfunction and eye movement disorders.
