Clinical Trials Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Apr 15, 2024; 15(4): 664-674
Published online Apr 15, 2024. doi: 10.4239/wjd.v15.i4.664
Effect of special types of bread with select herbal components on postprandial glucose levels in diabetic patients
Drasko M Gostiljac, Srdjan S Popovic, Vesna Dimitrijevic-Sreckovic, Sasa M Ilic, Jelena A Jevtovic, Dragan M Nikolic, Ivan A Soldatovic
Drasko M Gostiljac, Srdjan S Popovic, Vesna Dimitrijevic-Sreckovic, Sasa M Ilic, Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Centre of Serbia, Belgrade 11000, Serbia
Drasko M Gostiljac, Srdjan S Popovic, Vesna Dimitrijevic-Sreckovic, Dragan M Nikolic, Ivan A Soldatovic, Faculty of Medicine, University of Belgrade, Belgrade 11000, Serbia
Jelena A Jevtovic, Clinic for Gastroenterology and Hepatology, University Clinical Centre of Serbia, Belgrade 11000, Serbia
Dragan M Nikolic, Clinic for Endocrinology, Diabetes and Metabolic Diseases-Laboratory for Human Pancreatic Islets Culture, University Clinical Centre of Serbia, Belgrade 11000, Serbia
Author contributions: Gostiljac DM, Popovic SS and Dimitrijevic-Sreckovic V designed the research study; Gostiljac DM, Ilic SM and Jevtovic JA performed the research; Gostiljac DM, Soldatovic IA and Nikolic DM analyzed the data and wrote the manuscript; All authors have read and approve the final manuscript.
Institutional review board statement: All subjects provided informed consent for inclusion in the study. The investigation was carried out in accordance with the Declaration of Helsinki and was revised in 2013.
Clinical trial registration statement: The study is registered in the German Clinical Trials Register DRKS00023611. The clinical trial was registered after completion because the law of the Republic of Serbia does not require registration in the international registry.
Informed consent statement: All study participants, or their legal guardian, provided written consent prior to study enrollment.
Conflict-of-interest statement: All authors agree that there is no conflict of interest.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dragan M Nikolić, MD, PhD, Doctor, Research Associate, Science Editor, Faculty of Medicine, University of Belgrade, Dr Subotica 9, Belgrade 11000, Serbia. dragannikolic8@yahoo.com
Received: November 26, 2023
Peer-review started: November 26, 2023
First decision: December 17, 2023
Revised: January 8, 2024
Accepted: March 7, 2024
Article in press: March 7, 2024
Published online: April 15, 2024
Core Tip

Core Tip: We are testing special types of bread in populations with compromised glucoregulation. It is novel, tasty, and very effective in postprandial glucoregulation. In this study, we compared novel bread (TopiGluk) with standard hospital rye bread and obtained significant differences regarding glucose metabolism of TopiGluk compared to rye bread. This research might be interesting for readers because TopiGluk could become a standard supplement in bread for patients with compromised glucoregulation and those at high risk for diabetes.