Copyright ©2010 Baishideng.
World J Gastrointest Oncol. Aug 15, 2010; 2(8): 322-325
Published online Aug 15, 2010. doi: 10.4251/wjgo.v2.i8.322
Table 1 Alcohol and cancer: mutations and polymorphism genes
Ethanol metabolism (ADHs, ALDHs, CYP2E1, Mitochondrial Superoxide Dismutase, Myeloperoxidase)
Cytokines of inflammatory response: TNF α, TNF α promoter polymorphisms, IL1, IL10 (anti-inflammatory), TNF α type 1 receptor, CD14 receptor expression (Kupffer cell)
GABA-ergic, dopaminergic, serotoninergic systems
Polymorphisms in DNA repair genes: DNA ligase III, DNA polymerase b, poly (ADP ribose) polymerase
Components of immune systems (adaptive, innate)