Alcohol and gastrointestinal oncology

doi:10.4251/wjgo.v2.i8.322

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Aug 15, 2010 (publication date) through Nov 12, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Aug 15, 2010; 2(8): 322-325
Published online Aug 15, 2010. doi: 10.4251/wjgo.v2.i8.322

Table 1 Alcohol and cancer: mutations and polymorphism genes

Ethanol metabolism (ADHs, ALDHs, CYP2E1, Mitochondrial Superoxide Dismutase, Myeloperoxidase)

Cytokines of inflammatory response: TNF α, TNF α promoter polymorphisms, IL1, IL10 (anti-inflammatory), TNF α type 1 receptor, CD14 receptor expression (Kupffer cell)

GABA-ergic, dopaminergic, serotoninergic systems

Polymorphisms in DNA repair genes: DNA ligase III, DNA polymerase b, poly (ADP ribose) polymerase

Components of immune systems (adaptive, innate)

CYP2E1: Cytochrome P450 2E1; ADHs: alcohol dehydrogenases; ALDHs: Acetaldehyde dehydrogenases

Citation: Testino G, Borro P. Alcohol and gastrointestinal oncology. World J Gastrointest Oncol 2010; 2(8): 322-325
URL: https://www.wjgnet.com/1948-5204/full/v2/i8/322.htm
DOI: https://dx.doi.org/10.4251/wjgo.v2.i8.322