Alcohol and gastrointestinal oncology

doi:10.4251/wjgo.v2.i8.322

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Aug 15, 2010 (publication date) through Nov 8, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Aug 15, 2010; 2(8): 322-325
Published online Aug 15, 2010. doi: 10.4251/wjgo.v2.i8.322

Alcohol and gastrointestinal oncology

Gianni Testino, Paolo Borro

Gianni Testino, Paolo Borro, Department of Specialist Medicine, S. Martino Hospital, 16136 Genova, Italy

Author contributions: Testino G and Borro P wrote this paper.

Correspondence to: Gianni Testino, Professor, Department of Specialist Medicine, S. Martino Hospital, Via Ausonia 30/9, 16136 Genova, Italy. gianni.testino@hsanmartino.it

Telephone: +39-10-5552307 Fax: +39-10-5556738

Received: May 18, 2010
Revised: July 30, 2010
Accepted: August 6, 2010
Published online: August 15, 2010

Abstract

Results from several large epidemiological studies have firmly established that alcohol is associated with elevated cancer incidence and mortality. Recently the International Agency for Cancer Research stated that acetaldehyde associated with alcoholic beverages is carcinogenic to humans and confirmed the Group 1 classification of alcohol consumption and of ethanol in alcoholic beverages. Alcohol consumption causes cancers of the oral cavity, pharynx, larynx, oesophagus, colorectum, liver, pancreas and female breast. The frequency of most alcohol-induced diseases increases in a linear fashion as intake increases: oral, oesophagus and colon cancer fall into this pattern. Very little is known about safe margins of alcohol consumption. US Department of Health and Human Services suggest a maximum of 28 g of alcohol a day in man and half of this in women.

Keywords: Hepatology; Gastroenterology; Oncology; Cancer; Alcohol