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©The Author(s) 2022.
World J Gastrointest Oncol. Apr 15, 2022; 14(4): 820-832
Published online Apr 15, 2022. doi: 10.4251/wjgo.v14.i4.820
Published online Apr 15, 2022. doi: 10.4251/wjgo.v14.i4.820
Table 1 Main prognostic factors in patients with lung metastases from colorectal cancer
| Prognostic factor | Overall survival | Disease-free survival | ||
| Favorable | Negative | Favorable | Negative | |
| Number of metastases[23,68,71,76-78,86-90] | Single | Multiple | ||
| Preoperative CEA level[61,69,86,87] | < 4-5 ng/mL | > 4-5 ng/mL | ||
| pStage of CRC[71,79,86,87] | Local disease, low Tstage, absence of nodal involvement | Advanced p and T stage, nodal Involvement | ||
| Lung metastases appearance[23,61,69-71,87,91] | Metachronous lung metastases | Bilateral lung synchronous metastasis, past history of extra thoracic metastasis | Long DFI between CRC and first detection of pulmonary metastasis | Synchronous pulmonary metastasis and CRC |
| Pulmonary metastasis derivation from primary site of CRC[64] | Right colon | Left colon or rectum | Not investigated | Not investigated |
| Lung metastasis size (cm)[61,69,78,79] | < 2 cm | > 2 cm | Not investigated | Not investigated |
| Mediastinal lymph node metastasis[23,69,89] | Negative | Positive | Not investigated | Not investigated |
| Metabolic characteristics[61,79] | Lung metastasis PET negative | Lung metastasis PET positive | Lung metastasis PET negative | Lung metastasis PET positive |
| Distance between lesion and resection margin (cm)[79] | > 2 cm | < 2 cm | Not investigated | Not Investigated |
- Citation: Chiappetta M, Salvatore L, Congedo MT, Bensi M, De Luca V, Petracca Ciavarella L, Camarda F, Evangelista J, Valentini V, Tortora G, Margaritora S, Lococo F. Management of single pulmonary metastases from colorectal cancer: State of the art. World J Gastrointest Oncol 2022; 14(4): 820-832
- URL: https://www.wjgnet.com/1948-5204/full/v14/i4/820.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v14.i4.820