Opinion Review
Copyright ©The Author(s) 2023.
World J Gastrointest Oncol. May 15, 2023; 15(5): 700-712
Published online May 15, 2023. doi: 10.4251/wjgo.v15.i5.700
Figure 1
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Figure 1 A case of clinical complete response confirmed at pathology. A-C: A 61-year-old male patient with rectal cancer. Endoscopy (A) and magnetic resonance imaging (MRI) (B and C) findings staged a tumour of the low rectum (cT3aN1, mesorectal fascia negative, extramural venous invasion negative, pelvic nodes negative). The patient underwent neoadjuvant chemoradiotherapy; D-G: Restaging at 15 wk after the beginning of the neoadjuvant chemoradiotherapy showed a clinical complete response at endoscopy (D), MRI (E), endorectal ultrasound (F), and 18-fluorodeoxyglucose-computed tomography/positron emission tomography (G).
Figure 2
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Figure 2 A case of clinical complete response confirmed at pathology. A-C: A 57-year-old female patient with rectal cancer. Endoscopy (A) and magnetic resonance imaging (MRI) (B and C) findings staged a tumour of the low of rectum (cT3aN0 mesorectal fascia negative, extramural vascular invasion negative, pelvic nodes negative). The patient underwent neoadjuvant chemoradiotherapy; D-G: Restaging at 15 wk after the beginning of therapy showed a clinical complete response at endoscopy (D), MRI (E), endorectal ultrasound (F), and 18-fluorodeoxyglucose-computed tomography/positron emission tomography (G).
Figure 3
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Figure 3 A case of near clinical complete response confirmed at pathology (ypT1N0). A-C: An 84-year-old male patient with rectal cancer. Endoscopy (A) and magnetic resonance imaging (MRI) (B and C) staged a tumour of the low rectum (cT3aN0M0, mesorectal fascia negative, extramural vascular invasion negative, pelvic nodes negative). The patient underwent short-course radiotherapy; D-G: The restaging at 15 wk after the beginning of neoadjuvant radiotherapy showed a near clinical complete response at endoscopy (D), MRI (E and F), and endorectal ultrasound (G).
Figure 4
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Figure 4 A case of poor response confirmed at pathology (ypT2N0). A-C: A 42-year-old male with rectal cancer. Endoscopy (A) and MRI (B and C) staged a tumour of the middle rectum (cT3bN2, mesorectal fascia negative, extramural vascular invasion positive, pelvic nodes negative). The patient underwent total neoadjuvant therapy; D-F: Restaging at 20 wk after the beginning of neoadjuvant radiotherapy showed a poor response at endoscopy (D) and MRI (E and F).