Copyright
©The Author(s) 2020.
World J Gastrointest Oncol. Jun 15, 2020; 12(6): 619-631
Published online Jun 15, 2020. doi: 10.4251/wjgo.v12.i6.619
Published online Jun 15, 2020. doi: 10.4251/wjgo.v12.i6.619
Figure 1 Specific structural characteristics and biological functions of Septin 9.
A: Octamers formed by mammalian septin complexes; B: Function and role of Septin 9 in human malignant tumors. SEPT9: Septin 9; HIF-1: Hypoxia inducible factor-1; JNK: Jun N-terminal kinase.
Figure 2 Structure of the filaments containing Septins 7/9b/11 and Jun N-terminal kinase signaling pathway.
A: Structure of the filaments containing Septins 7/9b/11; B: Regulatory mechanism of Septin 9 in the development and progression of malignant tumors. HIF-1: Hypoxia inducible factor-1; JNK: Jun N-terminal kinase; EMT: Epithelial-mesenchymal transformation; MLL: Mixed-lineage leukemia.
- Citation: Sun J, Zheng MY, Li YW, Zhang SW. Structure and function of Septin 9 and its role in human malignant tumors. World J Gastrointest Oncol 2020; 12(6): 619-631
- URL: https://www.wjgnet.com/1948-5204/full/v12/i6/619.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v12.i6.619