Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Aug 15, 2021; 13(8): 943-958
Published online Aug 15, 2021. doi: 10.4251/wjgo.v13.i8.943
Development of a prognostic prediction model based on microRNA-1269a in esophageal cancer
Yong Yu, Kai-Ming Ren
Yong Yu, Department of Ophtalmology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
Kai-Ming Ren, Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, China
Author contributions: All authors contributed to this manuscript; Yu Y and Ren KM designed and coordinated the study, performed the experiments, acquired and analyzed data, and interpreted the data and wrote the manuscript; all authors approved the final version of the article.
Supported by The National Natural Science Foundation of China, No. 81570866; and the Outstanding Doctor Foundation of China Medical University, No. M0554.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee in The Shengjing Hospital of China Medical University.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kai-Ming Ren, MD, PhD, Professor, Department of Thoracic Surgery, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang 110004, Liaoning Province, China. renkmcmu@163.com
Received: April 8, 2021
Peer-review started: April 8, 2021
First decision: May 24, 2021
Revised: May 27, 2021
Accepted: July 9, 2021
Article in press: July 9, 2021
Published online: August 15, 2021
Processing time: 128 Days and 2.5 Hours
Core Tip

Core Tip: MicroRNA-1269a expression levels, along with cancer stage and age, were shown to have significant predictive capacity for overall survival and cancer-specific survival in esophageal cancer. Using these results, we developed an easy-to-use nomogram for clinical use.