Opinion Review
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jun 15, 2021; 13(6): 462-471
Published online Jun 15, 2021. doi: 10.4251/wjgo.v13.i6.462
Efficacy and safety of endoscopic resection in treatment of small gastric stromal tumors: A state-of-the-art review
Ze-Ming Chen, Min-Si Peng, Li-Sheng Wang, Zheng-Lei Xu
Ze-Ming Chen, Min-Si Peng, Li-Sheng Wang, Zheng-Lei Xu, Department of Gastroenterology, Shenzhen People’s Hospital, The Second Clinical Medical College, Jinan University, Shenzhen 518000, Guangdong Province, China
Author contributions: Xu ZL conceived the idea for the manuscript; all authors reviewed the literature and drafted the manuscript.
Supported by the Natural Science Foundation of Guangdong Province of China, No. 2018A0303130278.
Conflict-of-interest statement: The author declares no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zheng-Lei Xu, MD, Associate Professor, Chief Doctor, Department of Gastroenterology, Shenzhen People’s Hospital, The Second Clinical Medical College, Jinan University, No. 1017 Dongmen North Road, Shenzhen 518000, Guangdong Province, China. 78249073@qq.com
Received: February 11, 2021
Peer-review started: February 11, 2021
First decision: March 29, 2021
Revised: April 4, 2021
Accepted: April 20, 2021
Article in press: April 20, 2021
Published online: June 15, 2021
Processing time: 116 Days and 3 Hours
Core Tip

Core Tip: Gastric stromal tumors (GSTs) are all malignant, but generally, the smaller the diameter, the more likely the tumor is inert. However, GSTs smaller than 2 cm in diameter are also at risk of growing and becoming more malignant. Endoscopic treatment of GSTs smaller than 5 cm in diameter is comparable to surgical treatment. Early endoscopic resection is safe and effective when there are high risk factors for GSTs smaller than 2 cm in diameter or the patients cannot be followed regularly, and different endoscopic treatment methods can be selected according to the tumor site and depth.