Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Aug 15, 2020; 12(8): 893-902
Published online Aug 15, 2020. doi: 10.4251/wjgo.v12.i8.893
Published online Aug 15, 2020. doi: 10.4251/wjgo.v12.i8.893
Clinical and pathological characteristics and prognosis of 132 cases of rectal neuroendocrine tumors
Yong-Jun Yu, Yu-Wei Li, Yang Shi, Zhao Zhang, Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin 300121, China
Min-Ying Zheng, Shi-Wu Zhang, Department of Pathology, Tianjin Union Medical Center, Tianjin 300121, China
Author contributions: Zhang SW designed the study, interpreted the data, and contributed to manuscript writing; Yu YJ and Li YW collected and analyzed the data; Shi Y and Zhang Z collected, analyzed, and interpreted the data; Zheng MY collected the data and gave constructive comments on the manuscript; all authors approved the manuscript before submission.
Institutional review board statement: The Ethics Committee of Tianjin Union Medical Center approved related screening, treatment, data collection, and follow-up of these patients.
Conflict-of-interest statement: The authors declare that they have no conflict of interest related to this manuscript.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Shi-Wu Zhang, PhD, Director, Department of Pathology, Tianjin Union Medical Center, Hongqiao District, Jieyuan Road, Tianjin 300121, China. zhangshiwu666@aliyun.com
Received: March 4, 2020
Peer-review started: March 4, 2020
First decision: April 26, 2020
Revised: May 26, 2020
Accepted: July 19, 2020
Article in press: July 19, 2020
Published online: August 15, 2020
Processing time: 161 Days and 7.8 Hours
Peer-review started: March 4, 2020
First decision: April 26, 2020
Revised: May 26, 2020
Accepted: July 19, 2020
Article in press: July 19, 2020
Published online: August 15, 2020
Processing time: 161 Days and 7.8 Hours
Core Tip
Core tip: Tumor size and grade were the most significantly associated factors, and tumor size was the sole factor that was independently related to survival in a multivariate analysis. Patients with tumors larger than 2 cm had a ten-fold higher risk of death. Patients with advanced neuroendocrine carcinomas had a significantly decreased 5-year overall survival compared to patients with grades 1 and 2 disease.