Li Q, Huang LY, Xue HP. Comparison of prognostic factors in different age groups and prognostic significance of neutrophil-lymphocyte ratio in patients with gastric cancer. World J Gastrointest Oncol 2020; 12(10): 1146-1166 [PMID: 33133383 DOI: 10.4251/wjgo.v12.i10.1146]
Corresponding Author of This Article
Hui-Ping Xue, MD, Professor, Department of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 145 Middle Shandong Road, Shanghai 200001, China. xuehuiping@renji.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Oct 15, 2020; 12(10): 1146-1166 Published online Oct 15, 2020. doi: 10.4251/wjgo.v12.i10.1146
Comparison of prognostic factors in different age groups and prognostic significance of neutrophil-lymphocyte ratio in patients with gastric cancer
Qiong Li, Lin-Yi Huang, Hui-Ping Xue
Qiong Li, Lin-Yi Huang, Hui-Ping Xue, Department ofGastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China
Author contributions: Xue HP is the corresponding author of the article; Li Q and Huang LY contributed equally to the article; Li Q collected the data, performed statistical analysis, and wrote the draft manuscript; Huang LY collected required documents, performed statistical analysis, refined figures and tables, and supplemented the manuscript; Xue HP designed and supervised the research and revised the manuscript; all authors read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.
Informed consent statement: Informed consent was waived by the Ethics Committee of Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.
Conflict-of-interest statement: All of the authors have no financial relationship to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Ping Xue, MD, Professor, Department of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 145 Middle Shandong Road, Shanghai 200001, China. xuehuiping@renji.com
Received: June 4, 2020 Peer-review started: June 4, 2020 First decision: July 21, 2020 Revised: August 4, 2020 Accepted: September 2, 2020 Article in press: September 2, 2020 Published online: October 15, 2020 Processing time: 132 Days and 8.1 Hours
Core Tip
Core Tip: This is a retrospective study that explored the prognostic factors in different age groups and the prognostic significance of neutrophil-lymphocyte ratio in gastric cancer patients. We compared the clinicopathological features of patients in two age groups (< 70 years and ≥ 70 years), analyzed the prognostic factors, and performed a thorough meta-analysis. The findings indicated that the improvement of preoperative nutritional status may be beneficial to the prognosis in younger patients, while the alleviation of inflammatory status should be emphasized for older patients before surgery. The conclusion can provide reliable reference for clinicians to identify and rectify the independent prognostic influencing factors in gastric cancer patients.
