Scientometrics
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. May 15, 2024; 16(5): 2200-2218
Published online May 15, 2024. doi: 10.4251/wjgo.v16.i5.2200
Hotspots and trends of risk factors in gastric cancer: A visualization and bibliometric analysis
Meng Li, Ning Gao, Shao-Li Wang, Yu-Feng Guo, Zhen Liu
Meng Li, Shao-Li Wang, Zhen Liu, Department of Gastroenterology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
Ning Gao, Yu-Feng Guo, Department of Acupuncture and Moxibustion, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
Co-first authors: Meng Li and Ning Gao.
Co-corresponding authors: Yu-Feng Guo and Zhen Liu.
Author contributions: Guo YF and Liu Z contributed to the conception and design of the study; Wang SL is responsible for literature searching, data collection; Li M and Gao N are responsible for statistical analysis and charting; Li M and Gao N was drafted and revised the manuscript. All authors were involved in the critical review of the results and have contributed to, read, and approved the final manuscript. Liu Z and Guo YF coordinated the design and facilities for this study, provided multiple support in terms of personnel, materials and methods for the conduct of this study, and were responsible for all correspondence with the editorial board and readers. Therefore, Liu Z and Guo YF are listed as co-corresponding authors as the leaders of this study. Li M and Gao N were the main drafters and revisers of this manuscript, as well as assisting other authors with data organization, processing, and analysis. Their contributions to this study are highly valued by other researchers. Therefore, Li M and Gao N are listed as co-first authors.
Supported by Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences, No. CI2023C015YL; and National Natural Science Foundation of China, No. 82174352.
Conflict-of-interest statement: Authors declare that they have no competing interests.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Meng Li, PhD, Doctor, Department of Gastroenterology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange Street, Xicheng District, Beijing 100053, China. zyxyjslm@163.com
Received: January 19, 2024
Peer-review started: January 19, 2024
First decision: January 27, 2024
Revised: February 8, 2024
Accepted: March 11, 2024
Article in press: March 11, 2024
Published online: May 15, 2024
Processing time: 111 Days and 6.1 Hours
ARTICLE HIGHLIGHTS
Research background

The absence of specific symptoms in patients with gastric cancer (GC) causes great difficulties in early diagnosis of the disease, therefore, it is very valuable to clarify the risk factors for early diagnosis and treatment of GC and to improve the survival of GC.

Research motivation

Researchers have conducted a large number of studies on risk factors in GC. However, a summary of the current state of research is lacking.

Research objectives

This study was conducted to enable physicians to keep abreast of the latest research evidence in the clinical field and to make increasingly informed decisions.

Research methods

The articles covered in this study were obtained from the Web of Science database and the data were processed through CiteSpace and VOSviewer software.

Research results

A total of 2514 papers from 72 countries and 2507 research institutions were retrieved. China, National Cancer Center, and Shoichiro Tsugane were the most productive country, institution, or author, respectively. The research hotspots in the study of risk factors for GC are summarized in four areas, namely: Helicobacter pylori (H. pylori) infection, single nucleotide polymorphism, bio-diagnostic markers, and GC risk prediction models.

Research conclusions

A list of key risk factors for GC was also constructed, and we identified H. pylori infection, single-nucleotide polymorphism, smoking, diet, and alcohol as the most important risk factors for the development of GC, and proposed corresponding strategies for GC prevention.

Research perspectives

GC risk prediction modeling is the latest research hotspot and will likely be the future direction of research in the field.