Yin JJ, Hu X, Hu S, Sheng GH. Efficacy of multi-slice spiral computed tomography in evaluating gastric cancer recurrence after endoscopic submucosal dissection. World J Gastrointest Oncol 2023; 15(9): 1636-1643 [PMID: 37746651 DOI: 10.4251/wjgo.v15.i9.1636]
Corresponding Author of This Article
Xiao Hu, RN, Associate Chief Nurse, Department of Geriatrics, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, No. 19 Floor, Building 6, Huangshi 435000, Hubei Province, China. 11786356@qq.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Sep 15, 2023; 15(9): 1636-1643 Published online Sep 15, 2023. doi: 10.4251/wjgo.v15.i9.1636
Efficacy of multi-slice spiral computed tomography in evaluating gastric cancer recurrence after endoscopic submucosal dissection
Jian-Jun Yin, Xiao Hu, Sen Hu, Guo-Hong Sheng
Jian-Jun Yin, Sen Hu, Guo-Hong Sheng, Department of Radiology, Huangshi Maternity and Children's health Hospital, Affiliated Maternity and Children's Health Hospital of Hubei Polytechnic University, Huangshi 435000, Hubei Province, China
Xiao Hu, Department of Geriatrics, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi 435000, Hubei Province, China
Author contributions: Yin JJ and Hu X contributed equally to this work; Hu S designed the study; Sheng GH contributed to the analysis of the manuscript; Yin JJ and Hu X were involved in the data and writing of this article; and all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Huangshi Maternity and Children's health Hospital, Affiliated Maternity and Children's health Hospital of Hubei Polytechnic University, Huangshi, China, Institutional Review Board.
Informed consent statement: All study participants and their legal guardians provide informed written consent before the study recruitment.
Conflict-of-interest statement: All authors have no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao Hu, RN, Associate Chief Nurse, Department of Geriatrics, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, No. 19 Floor, Building 6, Huangshi 435000, Hubei Province, China. 11786356@qq.com
Received: July 4, 2023 Peer-review started: July 4, 2023 First decision: July 19, 2023 Revised: July 25, 2023 Accepted: August 8, 2023 Article in press: August 8, 2023 Published online: September 15, 2023 Processing time: 70 Days and 23.4 Hours
ARTICLE HIGHLIGHTS
Research background
There is an urgent need to develop a simple and easy approach for screening for early gastric cancer (EGC) recurrence in patients treated with endoscopic submucosal dissection (ESD).
Research motivation
Multi-slice spiral computed tomography (CT) is a quick, convenient and promising auxiliary examination. Enhanced spiral CT scan generates high resolution images, thus can provide a basis for the identification of gastric cancer lesions.
Research objectives
To explore the role of CT recurrence assessment in EGC patients who were treated with ESD.
Research methods
This retrospective study recruited patients from the endoscopy department between January 2002 and December 2015. Basic characteristics, symptoms, CT results, and endoscopy with biopsy findings were analyzed. Sensitivity, specificity, negative and positive predictive values of CT for recurrent gastric cancer were calculated. Arterial and venous CT values were evaluated using area under the curve (AUC) analysis, and receiver operating characteristic curve analysis compared their performance for detecting recurrent EGC. The diagnostic efficacy and accuracy of enhanced CT were assessed in comparison to gold standard techniques for detecting recurrent EGC.
Research results
The approach had sensitivity and specificity rates of 44.22% and 43.86%, respectively, which are far from satisfactory. AUC value of arterial and venous CT values for recurrent EGC was greater than 0.5, indicating that enhanced CT can predict EGC, albeit at low accuracy.
Research conclusions
Enhanced CT has superior diagnostic efficacy but lower accuracy than gold standard techniques in patients with recurrent EGC.
Research perspectives
Multi-slice spiral CT is valuable in EGC screening.
