Okamoto M, Maeda K, Yanagitani A, Tanaka K. Case of pseudo-Meigs' syndrome caused by gastric cancer-related metastatic ovarian tumor with prolonged survival. World J Gastrointest Oncol 2016; 8(11): 801-804 [PMID: 27895818 DOI: 10.4251/wjgo.v8.i11.801]
Corresponding Author of This Article
Masaru Okamoto, MD, Department of General Internal Medicine, Tottori Prefectural Central Hospital, Tottori, Edu, Tottori City, Tottori 680-0901, Japan. okamotoma@pref.tottori.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Masaru Okamoto, Department of General Internal Medicine, Tottori Prefectural Central Hospital, Tottori 680-0901, Japan
Kazunori Maeda, Atsushi Yanagitani, Kiwamu Tanaka, Department of Gastroenterology, Tottori Prefectural Central Hospital, Tottori 680-0901, Japan
Author contributions: Okamoto M, Maeda K, Yanagitani A and Tanaka K equally discussed the clinical manifestations; Maeda K, Yanagitani A and Tanaka K reviewed the manuscript critically; Okamoto M wrote the paper.
Institutional review board statement: Tottori Prefectural Central Hospital Clinical Ethics Review Board does not require approval for case reports.
Informed consent statement: The patient involved in this case report authorized the disclosure of her protected health information for academic purposes.
Conflict-of-interest statement: All authors have no conflicts of interests to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Masaru Okamoto, MD, Department of General Internal Medicine, Tottori Prefectural Central Hospital, Tottori, Edu, Tottori City, Tottori 680-0901, Japan. okamotoma@pref.tottori.jp
Telephone: +81-857-262271 Fax: +81-857-293227
Received: May 31, 2016 Peer-review started: June 1, 2016 First decision: August 10, 2016 Revised: August 25, 2016 Accepted: September 13, 2016 Article in press: September 18, 2016 Published online: November 15, 2016 Processing time: 166 Days and 20.8 Hours
Abstract
A 48-year-old woman presented with bilateral enlarged ovaries, ascites, bilateral pleural effusion, and advanced gastric cancer. Pleural fluid cytology did not reveal malignant cells. Oophorectomy, performed as a palliative procedure, was followed by rapid resolution of the pleural effusion and ascites. The patient was diagnosed with pseudo-Meigs’ syndrome, and underwent chemotherapy followed by partial gastrectomy. At the last follow-up, 84 mo following oophorectomy, she was alive, and free of disease recurrence, despite not receiving any further treatment. Pseudo-Meigs’ syndrome should be considered in patients with bilateral ovarian tumors, ascites and pleural effusion, and treatment such as oophorectomy may result in symptomatic improvement and better prognosis in similar patients.
Core tip: In general, the prognosis of gastric cancer with distant metastases is poor. On the other hand, oophorectomy for gastric cancer-related metastatic ovarian tumors may improve survival, especially in the absence of metastasis to other organs. We here report a long-term survival case of pseudo-Meigs’ syndrome caused by gastric cancer following oophorectomy. We conclude that pseudo-Meigs’ syndrome should be considered in patients with gastric cancer with enlarged ovaries, pleural effusion, and ascites.
