Zhang BX, Chen ZH, Liu Y, Zeng YJ, Li YC. Inflammatory pseudotumor-like follicular dendritic cell sarcoma: A brief report of two cases. World J Gastrointest Oncol 2019; 11(12): 1231-1239 [PMID: 31908727 DOI: 10.4251/wjgo.v11.i12.1231]
Corresponding Author of This Article
Yan-Chun Li, PhD, Doctor, Department of Pathology, People’s Hospital of Hunan Province, No. 61, Jiefang West Road, Changsha 410005, Hunan Province, China. lychglx@163.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Dec 15, 2019; 11(12): 1231-1239 Published online Dec 15, 2019. doi: 10.4251/wjgo.v11.i12.1231
Inflammatory pseudotumor-like follicular dendritic cell sarcoma: A brief report of two cases
Bi-Xi Zhang, Zhi-Hong Chen, Yu Liu, Yuan-Jun Zeng, Yan-Chun Li
Bi-Xi Zhang, Zhi-Hong Chen, Yu Liu, Yuan-Jun Zeng, Yan-Chun Li, Department of Pathology, People’s Hospital of Hunan Province, Changsha 410005, Hunan Province, China
Author contributions: All authors contributed to the study; Zhang BX wrote the manuscript; Chen ZH, Liu Y, Zeng YJ, and Li YC collected and analysed the data and contributed to the follow-up results; all authors read and approved the final manuscript.
Informed consent statement: All study participants, or their legal guardian, provided written informed consent prior to the study.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Yan-Chun Li, PhD, Doctor, Department of Pathology, People’s Hospital of Hunan Province, No. 61, Jiefang West Road, Changsha 410005, Hunan Province, China. lychglx@163.com
Telephone: +86-731-83929288
Received: February 20, 2019 Peer-review started: February 22, 2019 First decision: June 4, 2019 Revised: September 1, 2019 Accepted: September 26, 2019 Article in press: September 26, 2019 Published online: December 15, 2019 Processing time: 292 Days and 21.5 Hours
Abstract
BACKGROUND
Follicular dendritic cell (FDC) sarcoma/tumor is a rare malignant tumor of follicular dendritic cells, which is considered a low-grade sarcoma that can involve lymph nodes or extranodal sites. Conventional FDC sarcomas are negative for Epstein-Barr virus (EBV), whereas the inflammatory pseudotumor-like variant consistently shows EBV in the neoplastic cells.
CASE SUMMARY
We report two cases of inflammatory pseudotumor-like FDC sarcoma in the liver that received 3D laparoscopic right hepatectomy and open right hepatectomy separately.
CONCLUSION
EBV probe-based in situ hybridization and detection of immunohistochemical markers of FDC play an important role in the diagnosis and differential diagnosis of inflammatory pseudotumor-like FDC sarcoma. Complete surgical excision combined with regional lymphadenectomy may be effective in reducing the postoperative recurrence and metastasis and improving long-term survival rates.
Core tip: There have been 48 previously reported cases of inflammatory pseudotumor-like follicular dendritic cell (FDC) sarcoma, which occurs almost exclusively in the liver and spleen. Here we report two cases of inflammatory pseudotumor-like FDC sarcoma in the liver that were treated by 3D laparoscopic right hepatectomy and open right hepatectomy separately.
